Testosterone is an endogenous regulator of BAFF and splenic B cell number
Testosterone deficiency is associated with autoimmunity and increased B cell numbers, but the underlying mechanism is unclear. Here the authors show that testosterone may modulate the production of B cell survival factor BAFF by fibroblastic reticular cells via regulation of splenic neurotransmitter...
Πλήρης περιγραφή
Λεπτομέρειες βιβλιογραφικής εγγραφής
| Κύριοι συγγραφείς: |
Anna S. Wilhelmson,
Marta Lantero Rodriguez,
Alexandra Stubelius,
Per Fogelstrand,
Inger Johansson,
Matthew B. Buechler,
Steve Lianoglou,
Varun N. Kapoor,
Maria E. Johansson,
Johan B. Fagman,
Amanda Duhlin,
Prabhanshu Tripathi,
Alessandro Camponeschi,
Bo T. Porse,
Antonius G. Rolink,
Hans Nissbrandt,
Shannon J. Turley,
Hans Carlsten,
Inga-Lill Mårtensson,
Mikael C. I. Karlsson,
Åsa Tivesten |
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| Μορφή: | Άρθρο
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| Γλώσσα: | English |
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| Έκδοση: |
Nature Portfolio
2018-05-01
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| Σειρά: | Nature Communications
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| Διαθέσιμο Online: | https://doi.org/10.1038/s41467-018-04408-0
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