Testosterone is an endogenous regulator of BAFF and splenic B cell number
Testosterone deficiency is associated with autoimmunity and increased B cell numbers, but the underlying mechanism is unclear. Here the authors show that testosterone may modulate the production of B cell survival factor BAFF by fibroblastic reticular cells via regulation of splenic neurotransmitter...
Полное описание
Библиографические подробности
| Главные авторы: |
Anna S. Wilhelmson,
Marta Lantero Rodriguez,
Alexandra Stubelius,
Per Fogelstrand,
Inger Johansson,
Matthew B. Buechler,
Steve Lianoglou,
Varun N. Kapoor,
Maria E. Johansson,
Johan B. Fagman,
Amanda Duhlin,
Prabhanshu Tripathi,
Alessandro Camponeschi,
Bo T. Porse,
Antonius G. Rolink,
Hans Nissbrandt,
Shannon J. Turley,
Hans Carlsten,
Inga-Lill Mårtensson,
Mikael C. I. Karlsson,
Åsa Tivesten |
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| Формат: | Статья
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| Язык: | English |
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| Опубликовано: |
Nature Portfolio
2018-05-01
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| Серии: | Nature Communications
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| Online-ссылка: | https://doi.org/10.1038/s41467-018-04408-0
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