Testosterone is an endogenous regulator of BAFF and splenic B cell number

Testosterone is an endogenous regulator of BAFF and splenic B cell number

Testosterone deficiency is associated with autoimmunity and increased B cell numbers, but the underlying mechanism is unclear. Here the authors show that testosterone may modulate the production of B cell survival factor BAFF by fibroblastic reticular cells via regulation of splenic neurotransmitter...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Anna S. Wilhelmson, Marta Lantero Rodriguez, Alexandra Stubelius, Per Fogelstrand, Inger Johansson, Matthew B. Buechler, Steve Lianoglou, Varun N. Kapoor, Maria E. Johansson, Johan B. Fagman, Amanda Duhlin, Prabhanshu Tripathi, Alessandro Camponeschi, Bo T. Porse, Antonius G. Rolink, Hans Nissbrandt, Shannon J. Turley, Hans Carlsten, Inga-Lill Mårtensson, Mikael C. I. Karlsson, Åsa Tivesten
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Nature Portfolio 2018-05-01
Σειρά:Nature Communications
Διαθέσιμο Online:https://doi.org/10.1038/s41467-018-04408-0

Διαδίκτυο

https://doi.org/10.1038/s41467-018-04408-0

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