Testosterone is an endogenous regulator of BAFF and splenic B cell number
Testosterone deficiency is associated with autoimmunity and increased B cell numbers, but the underlying mechanism is unclear. Here the authors show that testosterone may modulate the production of B cell survival factor BAFF by fibroblastic reticular cells via regulation of splenic neurotransmitter...
Հիմնական հեղինակներ: | , , , , , , , , , , , , , , , , , , , , |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
Nature Portfolio
2018-05-01
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Շարք: | Nature Communications |
Առցանց հասանելիություն: | https://doi.org/10.1038/s41467-018-04408-0 |