5‐Hydroxymethylfurfural reduces skeletal muscle superoxide production and modifies force production in rats exposed to hypobaric hypoxia

5‐Hydroxymethylfurfural reduces skeletal muscle superoxide production and modifies force production in rats exposed to hypobaric hypoxia

Abstract Decreased blood‐tissue oxygenation at high altitude (HA) increases mitochondrial oxidant production and reduces exercise capacity. 5‐Hydroxymethylfurfural (5‐HMF) is an antioxidant that increases hemoglobin's binding affinity for oxygen. For these reasons, we hypothesized that 5‐HMF wo...

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Bibliographic Details
Main Authors: Geoffrey E. Ciarlone, Joshua M. Swift, Brian T. Williams, Richard T. Mahon, Nicholas G. Roney, Tianzheng Yu, Heath G. Gasier
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Physiological Reports
Subjects:
antioxidants
high altitude
mitochondria
oxidant stress
Online Access:https://doi.org/10.14814/phy2.15743

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