Intestinal Epithelial Cell Exosome Launches IL-1β-Mediated Neuron Injury in Sepsis-Associated Encephalopathy

Intestinal Epithelial Cell Exosome Launches IL-1β-Mediated Neuron Injury in Sepsis-Associated Encephalopathy

BackgroundGut–microbiota–brain axis links the relationship between intestinal microbiota and sepsis-associated encephalopathy (SAE). However, the key mediators between them remain unclear.MethodsMemory test was determined by Water maze. Intestinal flora was measured by 16S RNA sequencing. Neurotrans...

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Bibliographic Details
Main Authors:	Shaosong Xi, Yunguang Wang, Chenghao Wu, Weihua Peng, Ying Zhu, Wei Hu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-01-01
Series:	Frontiers in Cellular and Infection Microbiology
Subjects:	intestinal epithelial cell exosome sepsis-associated encephalopathy fecal microbiota transplantation IL-1β mesenteric lymph nodes
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2021.783049/full

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