Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivatives
2-Oxo-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-6-phenylpyridin-3-carbnitriles (2a–c) and its derivatives containing 1,2,4-triazole (4a–c), thiazolo[3,2-b][1,2,4]triazole (5a–c), hydrazide (6a–c), pyrazolones (7a–c) and (8a–c) were synthesized. Structures of all these previously unknown compounds...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-09-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535211001638 |
| _version_ | 1818529361792335872 |
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| author | Anand Raghunath Saundane Yarlakatti Manjunatha |
| author_facet | Anand Raghunath Saundane Yarlakatti Manjunatha |
| author_sort | Anand Raghunath Saundane |
| collection | DOAJ |
| description | 2-Oxo-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-6-phenylpyridin-3-carbnitriles (2a–c) and its derivatives containing 1,2,4-triazole (4a–c), thiazolo[3,2-b][1,2,4]triazole (5a–c), hydrazide (6a–c), pyrazolones (7a–c) and (8a–c) were synthesized. Structures of all these previously unknown compounds were confirmed by their spectral studies and elemental analysis. The compounds were screened for their antioxidant and antimicrobial activities. |
| first_indexed | 2024-12-11T17:05:54Z |
| format | Article |
| id | doaj.art-d1fdb79b1c0a441eaf0bb9711b940bfa |
| institution | Directory Open Access Journal |
| issn | 1878-5352 |
| language | English |
| last_indexed | 2024-12-11T17:05:54Z |
| publishDate | 2016-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Arabian Journal of Chemistry |
| spelling | doaj.art-d1fdb79b1c0a441eaf0bb9711b940bfa2022-12-22T00:57:42ZengElsevierArabian Journal of Chemistry1878-53522016-09-019S1S501S50910.1016/j.arabjc.2011.06.011Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivativesAnand Raghunath SaundaneYarlakatti Manjunatha2-Oxo-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-6-phenylpyridin-3-carbnitriles (2a–c) and its derivatives containing 1,2,4-triazole (4a–c), thiazolo[3,2-b][1,2,4]triazole (5a–c), hydrazide (6a–c), pyrazolones (7a–c) and (8a–c) were synthesized. Structures of all these previously unknown compounds were confirmed by their spectral studies and elemental analysis. The compounds were screened for their antioxidant and antimicrobial activities.http://www.sciencedirect.com/science/article/pii/S1878535211001638IndolePyridineThiazolo[3,2-b][1,2,4]triazolePyrazoleAntioxidantAntimicrobial activity |
| spellingShingle | Anand Raghunath Saundane Yarlakatti Manjunatha Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivatives Arabian Journal of Chemistry Indole Pyridine Thiazolo[3,2-b][1,2,4]triazole Pyrazole Antioxidant Antimicrobial activity |
| title | Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivatives |
| title_full | Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivatives |
| title_fullStr | Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivatives |
| title_full_unstemmed | Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivatives |
| title_short | Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivatives |
| title_sort | synthesis antimicrobial and antioxidant activities of 2 oxo 6 phenyl 2 yl 4 2 phenyl 5 substituted 1h indol 3 yl 1 2 dihydro pyridin 3 carbonitriles and their derivatives |
| topic | Indole Pyridine Thiazolo[3,2-b][1,2,4]triazole Pyrazole Antioxidant Antimicrobial activity |
| url | http://www.sciencedirect.com/science/article/pii/S1878535211001638 |
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