Nonlinear Association between Physical Function and Risk of Mild Cognitive Impairment in Older Women with Low Muscle Mass
PURPOSE This study aimed to determine the nonlinear relationship between physical function and body composition in older women with mild cognitive impairment (MCI) and low muscle mass (LMM). Early prediction of sarcopenic MCI is important; however, it remains unclear whether improvements in physical...
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| Format: | Article |
| Language: | Korean |
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The Korean Society of Exercise Physiology
2022-11-01
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| Series: | 운동과학 |
| Subjects: | |
| Online Access: | http://www.ksep-es.org/upload/pdf/ksep-2022-00521.pdf |
| _version_ | 1797871261800464384 |
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| author | Ja-Gyeong Yang Gwon-Min Kim Seongryu Bae Hyuntae Park |
| author_facet | Ja-Gyeong Yang Gwon-Min Kim Seongryu Bae Hyuntae Park |
| author_sort | Ja-Gyeong Yang |
| collection | DOAJ |
| description | PURPOSE This study aimed to determine the nonlinear relationship between physical function and body composition in older women with mild cognitive impairment (MCI) and low muscle mass (LMM). Early prediction of sarcopenic MCI is important; however, it remains unclear whether improvements in physical function and cell health promote low rates of sarcopenic MCI in community settings. METHODS A total of 120 older women were enrolled, and subsequently stratified into the LMM group (n=90) and MCI with LMM group (n=30). MCI was evaluated by a clinician based on global cognitive function and clinical findings. RESULTS The results of hand grip strength (HGS), short-physical performance battery (SPPB), and 6-minute walk test (6 MWT) were found to be linearly associated with the risk of MCI. This result indicates that endurance capacity in the LMM with MCI group had an adjusted odds ratio of 3.69 (95% CI: 1.11–12.18). The nonlinearity of physical function on the risk of MCI was analyzed using the generalized additive models (GAM). CONCLUSIONS Physical function and body composition is significantly associated with LMM and MCI risk in aging adults. It is expected that the evaluation and improvement of kinematic indicators, such as HGS, SPPB, endurance, and PhA, could contribute to the prediction and prevention of MCI. |
| first_indexed | 2024-04-10T00:40:02Z |
| format | Article |
| id | doaj.art-d20088bce03b43a09fd8be64d29e97da |
| institution | Directory Open Access Journal |
| issn | 1226-1726 2384-0544 |
| language | Korean |
| last_indexed | 2024-04-10T00:40:02Z |
| publishDate | 2022-11-01 |
| publisher | The Korean Society of Exercise Physiology |
| record_format | Article |
| series | 운동과학 |
| spelling | doaj.art-d20088bce03b43a09fd8be64d29e97da2023-03-14T07:08:07ZkorThe Korean Society of Exercise Physiology운동과학1226-17262384-05442022-11-0131452753610.15857/ksep.2022.005211011Nonlinear Association between Physical Function and Risk of Mild Cognitive Impairment in Older Women with Low Muscle MassJa-Gyeong Yang0Gwon-Min Kim1Seongryu Bae2Hyuntae Park3 Department of Healthcare and Science, Dong-A University, Busan, Korea Medical Research Institute, Pusan National University, Busan, Korea Department of Healthcare and Science, Dong-A University, Busan, Korea Department of Healthcare and Science, Dong-A University, Busan, KoreaPURPOSE This study aimed to determine the nonlinear relationship between physical function and body composition in older women with mild cognitive impairment (MCI) and low muscle mass (LMM). Early prediction of sarcopenic MCI is important; however, it remains unclear whether improvements in physical function and cell health promote low rates of sarcopenic MCI in community settings. METHODS A total of 120 older women were enrolled, and subsequently stratified into the LMM group (n=90) and MCI with LMM group (n=30). MCI was evaluated by a clinician based on global cognitive function and clinical findings. RESULTS The results of hand grip strength (HGS), short-physical performance battery (SPPB), and 6-minute walk test (6 MWT) were found to be linearly associated with the risk of MCI. This result indicates that endurance capacity in the LMM with MCI group had an adjusted odds ratio of 3.69 (95% CI: 1.11–12.18). The nonlinearity of physical function on the risk of MCI was analyzed using the generalized additive models (GAM). CONCLUSIONS Physical function and body composition is significantly associated with LMM and MCI risk in aging adults. It is expected that the evaluation and improvement of kinematic indicators, such as HGS, SPPB, endurance, and PhA, could contribute to the prediction and prevention of MCI.http://www.ksep-es.org/upload/pdf/ksep-2022-00521.pdfmild cognitive impairmentphase anglelow muscle massphysical functionolder women |
| spellingShingle | Ja-Gyeong Yang Gwon-Min Kim Seongryu Bae Hyuntae Park Nonlinear Association between Physical Function and Risk of Mild Cognitive Impairment in Older Women with Low Muscle Mass 운동과학 mild cognitive impairment phase angle low muscle mass physical function older women |
| title | Nonlinear Association between Physical Function and Risk of Mild Cognitive Impairment in Older Women with Low Muscle Mass |
| title_full | Nonlinear Association between Physical Function and Risk of Mild Cognitive Impairment in Older Women with Low Muscle Mass |
| title_fullStr | Nonlinear Association between Physical Function and Risk of Mild Cognitive Impairment in Older Women with Low Muscle Mass |
| title_full_unstemmed | Nonlinear Association between Physical Function and Risk of Mild Cognitive Impairment in Older Women with Low Muscle Mass |
| title_short | Nonlinear Association between Physical Function and Risk of Mild Cognitive Impairment in Older Women with Low Muscle Mass |
| title_sort | nonlinear association between physical function and risk of mild cognitive impairment in older women with low muscle mass |
| topic | mild cognitive impairment phase angle low muscle mass physical function older women |
| url | http://www.ksep-es.org/upload/pdf/ksep-2022-00521.pdf |
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