Impact of environmental noise exposure as an inducing factor on the prognosis of sudden sensorineural hearing loss: a retrospective case–control study
ObjectiveThe study aimed to evaluate the clinical characteristics and prognostic factors associated with unilateral sudden sensorineural hearing loss (SSNHL) related to environmental noise exposure before its onset.MethodsA total of 50 unilateral SSNHL patients exposed to environmental noise before...
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| Format: | Article |
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Frontiers Media S.A.
2023-06-01
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| Series: | Frontiers in Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2023.1210291/full |
| _version_ | 1827913550663778304 |
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| author | Yingjun Wang Yingjun Wang Wenping Xiong Wenping Xiong Xiao Sun Xiao Sun Kunpeng Lu Kunpeng Lu Fujia Duan Fujia Duan Haibo Wang Haibo Wang Mingming Wang Mingming Wang |
| author_facet | Yingjun Wang Yingjun Wang Wenping Xiong Wenping Xiong Xiao Sun Xiao Sun Kunpeng Lu Kunpeng Lu Fujia Duan Fujia Duan Haibo Wang Haibo Wang Mingming Wang Mingming Wang |
| author_sort | Yingjun Wang |
| collection | DOAJ |
| description | ObjectiveThe study aimed to evaluate the clinical characteristics and prognostic factors associated with unilateral sudden sensorineural hearing loss (SSNHL) related to environmental noise exposure before its onset.MethodsA total of 50 unilateral SSNHL patients exposed to environmental noise before onset (case group) and 924 unilateral SSNHL patients without any exposure to obvious inducing factors before onset (control group) were enrolled between January 2018 and October 2022. We retrospectively analyzed differences between both groups using the chi-square test, Fisher's exact tests, independent t-tests, and Mann–Whitney U-tests as appropriate before and after propensity score matching (PSM) based on sex, age, and initial pure-tone average (PTA). Prognostic factors for the case group were analyzed using univariate and multivariate logistic analyses between the effective and ineffective groups.ResultsBefore PSM, significant differences were noted in age, sex, time to treatment, the proportion of combined diabetes mellitus, initial PTA, hearing gain, the incidence of vertigo or aural fulness, the rate of vestibular dysfunction or inner ear MRI abnormalities, the effective rate, the glucose and homocysteine levels, and the proportion of audiogram curve types (P < 0.05) between both groups. After PSM, compared to the control group, a longer time to treatment (Z= −3.02, P < 0.05), higher final PTA (Z= −2.39, P < 0.05), lower hearing gain (Z= −3.46, P < 0.05), lower rate of vestibular dysfunction (χ2 = 55.1, P < 0.001), and lower effective rate (χ2 = 4.87, P < 0.05) were observed in the case group. There was a significant difference between the audiogram curve types in both groups (χ2 = 14.9, P < 0.05). Time to treatment (95% confidence interval: 0.692–0.965, P < 0.05) and final PTA (95% confidence interval: 0.921–0.998, P < 0.05) were associated with the clinical outcomes for the case group.ConclusionUnilateral SSNHL patients exposed to environmental noise triggers before onset showed a poorer effective rate and a lower rate of vestibular dysfunction than those who were not. The time to treatment and final PTA were associated with the prognosis of these patients. |
| first_indexed | 2024-03-13T02:31:31Z |
| format | Article |
| id | doaj.art-d20803d311d649e691e1088bd334d8e5 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-03-13T02:31:31Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Neuroscience |
| spelling | doaj.art-d20803d311d649e691e1088bd334d8e52023-06-29T14:11:49ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2023-06-011710.3389/fnins.2023.12102911210291Impact of environmental noise exposure as an inducing factor on the prognosis of sudden sensorineural hearing loss: a retrospective case–control studyYingjun Wang0Yingjun Wang1Wenping Xiong2Wenping Xiong3Xiao Sun4Xiao Sun5Kunpeng Lu6Kunpeng Lu7Fujia Duan8Fujia Duan9Haibo Wang10Haibo Wang11Mingming Wang12Mingming Wang13Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otology Medicine, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otology Medicine, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otology Medicine, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otology Medicine, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otology Medicine, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otology Center, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaDepartment of Otology Medicine, Shandong Provincial ENT Hospital, Shandong University, Jinan, ChinaObjectiveThe study aimed to evaluate the clinical characteristics and prognostic factors associated with unilateral sudden sensorineural hearing loss (SSNHL) related to environmental noise exposure before its onset.MethodsA total of 50 unilateral SSNHL patients exposed to environmental noise before onset (case group) and 924 unilateral SSNHL patients without any exposure to obvious inducing factors before onset (control group) were enrolled between January 2018 and October 2022. We retrospectively analyzed differences between both groups using the chi-square test, Fisher's exact tests, independent t-tests, and Mann–Whitney U-tests as appropriate before and after propensity score matching (PSM) based on sex, age, and initial pure-tone average (PTA). Prognostic factors for the case group were analyzed using univariate and multivariate logistic analyses between the effective and ineffective groups.ResultsBefore PSM, significant differences were noted in age, sex, time to treatment, the proportion of combined diabetes mellitus, initial PTA, hearing gain, the incidence of vertigo or aural fulness, the rate of vestibular dysfunction or inner ear MRI abnormalities, the effective rate, the glucose and homocysteine levels, and the proportion of audiogram curve types (P < 0.05) between both groups. After PSM, compared to the control group, a longer time to treatment (Z= −3.02, P < 0.05), higher final PTA (Z= −2.39, P < 0.05), lower hearing gain (Z= −3.46, P < 0.05), lower rate of vestibular dysfunction (χ2 = 55.1, P < 0.001), and lower effective rate (χ2 = 4.87, P < 0.05) were observed in the case group. There was a significant difference between the audiogram curve types in both groups (χ2 = 14.9, P < 0.05). Time to treatment (95% confidence interval: 0.692–0.965, P < 0.05) and final PTA (95% confidence interval: 0.921–0.998, P < 0.05) were associated with the clinical outcomes for the case group.ConclusionUnilateral SSNHL patients exposed to environmental noise triggers before onset showed a poorer effective rate and a lower rate of vestibular dysfunction than those who were not. The time to treatment and final PTA were associated with the prognosis of these patients.https://www.frontiersin.org/articles/10.3389/fnins.2023.1210291/fullsudden sensorineural hearing losshearing lossenvironmental noisenoise exposureprognosis |
| spellingShingle | Yingjun Wang Yingjun Wang Wenping Xiong Wenping Xiong Xiao Sun Xiao Sun Kunpeng Lu Kunpeng Lu Fujia Duan Fujia Duan Haibo Wang Haibo Wang Mingming Wang Mingming Wang Impact of environmental noise exposure as an inducing factor on the prognosis of sudden sensorineural hearing loss: a retrospective case–control study Frontiers in Neuroscience sudden sensorineural hearing loss hearing loss environmental noise noise exposure prognosis |
| title | Impact of environmental noise exposure as an inducing factor on the prognosis of sudden sensorineural hearing loss: a retrospective case–control study |
| title_full | Impact of environmental noise exposure as an inducing factor on the prognosis of sudden sensorineural hearing loss: a retrospective case–control study |
| title_fullStr | Impact of environmental noise exposure as an inducing factor on the prognosis of sudden sensorineural hearing loss: a retrospective case–control study |
| title_full_unstemmed | Impact of environmental noise exposure as an inducing factor on the prognosis of sudden sensorineural hearing loss: a retrospective case–control study |
| title_short | Impact of environmental noise exposure as an inducing factor on the prognosis of sudden sensorineural hearing loss: a retrospective case–control study |
| title_sort | impact of environmental noise exposure as an inducing factor on the prognosis of sudden sensorineural hearing loss a retrospective case control study |
| topic | sudden sensorineural hearing loss hearing loss environmental noise noise exposure prognosis |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2023.1210291/full |
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