Chitosan – Polyphosphate nanoparticles for a targeted drug release at the absorption membrane

Chitosan – Polyphosphate nanoparticles for a targeted drug release at the absorption membrane

The aim of this study was to develop nanoparticles (NPs) providing a targeted drug release directly on the epithelium of the intestinal mucosa.NPs were prepared via ionic gelation between cationic chitosan (Cs) and anionic polyphosphate (PP). The resulting NPs were characterized by their size, polyd...

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Bibliographic Details
Main Authors: Ahmad Saleh, Zeynep Burcu Akkuş-Dağdeviren, Julian David Friedl, Patrick Knoll, Andreas Bernkop-Schnürch
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Heliyon
Subjects:
Chitosan
Polyphosphate
Polymeric nanoparticles
Drug delivery
Targeted release
Alkaline phosphatase
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022018655

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