Research Progress on Fingerprint Analysis and Profile-Effect Relationship of Polysaccharides

Fingerprinting technique is a comprehensive method to evaluate the chemical components in complex system, and it plays an important role in the identification and quality control of Chinese herbal medicines. Polysaccharide fingerprints including chromatographic and spectroscopic technical analysis c...

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Main Authors: Jing LIU, Qingjiu TANG, Jingsong ZHANG, Jie FENG, Yanfang LIU
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2022-02-01
Series:Shipin gongye ke-ji
Subjects:
Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021010244
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author Jing LIU
Qingjiu TANG
Jingsong ZHANG
Jie FENG
Yanfang LIU
author_facet Jing LIU
Qingjiu TANG
Jingsong ZHANG
Jie FENG
Yanfang LIU
author_sort Jing LIU
collection DOAJ
description Fingerprinting technique is a comprehensive method to evaluate the chemical components in complex system, and it plays an important role in the identification and quality control of Chinese herbal medicines. Polysaccharide fingerprints including chromatographic and spectroscopic technical analysis can effectively evaluate the quality of polysaccharides by characterizing the structural characteristics of polysaccharides and exploring the spectrum-effect relationship of polysaccharide combining with activity studies. In this paper, the spectroscopic fingerprints analysis (infrared spectroscopy and nuclear magnetic resonance spectroscopy) for characterizing the structure of polysaccharides and the chromatographic fingerprints analysis for analyzing the molecular weight distribution (high performance size exclusion chromatography) and the hydrolysates (high performance liquid chromatography, high performance anion exchange chromatography, high performance thin layer chromatography and carbohydrate gel electrophoresis etc.) of polysaccharides are generalized, and the studies on profile-effect relationship of polysaccharides are summarized as well. Moreover, the prospect of the polysaccharide fingerprint is discussed, aiming to provide reference for further studies on fingerprint analysis and quality control of polysaccharides, and therefore to promote the development and utilization of polysaccharides.
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spelling doaj.art-d20a9ce4ca0d40068846c20a3888ce242022-12-22T02:52:35ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062022-02-0143440441210.13386/j.issn1002-0306.20210102442021010244-4Research Progress on Fingerprint Analysis and Profile-Effect Relationship of PolysaccharidesJing LIU0Qingjiu TANG1Jingsong ZHANG2Jie FENG3Yanfang LIU4Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P.R. China, National Engineering Research Centre of Edible Fungi, Key Laboratory of Agricultural Genetics and Breeding of Shanghai, Shanghai 201403, ChinaInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P.R. China, National Engineering Research Centre of Edible Fungi, Key Laboratory of Agricultural Genetics and Breeding of Shanghai, Shanghai 201403, ChinaInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P.R. China, National Engineering Research Centre of Edible Fungi, Key Laboratory of Agricultural Genetics and Breeding of Shanghai, Shanghai 201403, ChinaInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P.R. China, National Engineering Research Centre of Edible Fungi, Key Laboratory of Agricultural Genetics and Breeding of Shanghai, Shanghai 201403, ChinaInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Key Laboratory of Edible Fungi Resources and Utilization (South), Ministry of Agriculture, P.R. China, National Engineering Research Centre of Edible Fungi, Key Laboratory of Agricultural Genetics and Breeding of Shanghai, Shanghai 201403, ChinaFingerprinting technique is a comprehensive method to evaluate the chemical components in complex system, and it plays an important role in the identification and quality control of Chinese herbal medicines. Polysaccharide fingerprints including chromatographic and spectroscopic technical analysis can effectively evaluate the quality of polysaccharides by characterizing the structural characteristics of polysaccharides and exploring the spectrum-effect relationship of polysaccharide combining with activity studies. In this paper, the spectroscopic fingerprints analysis (infrared spectroscopy and nuclear magnetic resonance spectroscopy) for characterizing the structure of polysaccharides and the chromatographic fingerprints analysis for analyzing the molecular weight distribution (high performance size exclusion chromatography) and the hydrolysates (high performance liquid chromatography, high performance anion exchange chromatography, high performance thin layer chromatography and carbohydrate gel electrophoresis etc.) of polysaccharides are generalized, and the studies on profile-effect relationship of polysaccharides are summarized as well. Moreover, the prospect of the polysaccharide fingerprint is discussed, aiming to provide reference for further studies on fingerprint analysis and quality control of polysaccharides, and therefore to promote the development and utilization of polysaccharides.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021010244polysaccharidehydrolysatefingerprintprofile-effect relationshipquality control
spellingShingle Jing LIU
Qingjiu TANG
Jingsong ZHANG
Jie FENG
Yanfang LIU
Research Progress on Fingerprint Analysis and Profile-Effect Relationship of Polysaccharides
Shipin gongye ke-ji
polysaccharide
hydrolysate
fingerprint
profile-effect relationship
quality control
title Research Progress on Fingerprint Analysis and Profile-Effect Relationship of Polysaccharides
title_full Research Progress on Fingerprint Analysis and Profile-Effect Relationship of Polysaccharides
title_fullStr Research Progress on Fingerprint Analysis and Profile-Effect Relationship of Polysaccharides
title_full_unstemmed Research Progress on Fingerprint Analysis and Profile-Effect Relationship of Polysaccharides
title_short Research Progress on Fingerprint Analysis and Profile-Effect Relationship of Polysaccharides
title_sort research progress on fingerprint analysis and profile effect relationship of polysaccharides
topic polysaccharide
hydrolysate
fingerprint
profile-effect relationship
quality control
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021010244
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AT jiefeng researchprogressonfingerprintanalysisandprofileeffectrelationshipofpolysaccharides
AT yanfangliu researchprogressonfingerprintanalysisandprofileeffectrelationshipofpolysaccharides