Traditional Chinese medicine practices used in COVID-19 (Sars-cov 2/Coronavirus-19) treatment in clinic and their effects on the cardiovascular system
Objective: The aim of this study was to evaluate the effectiveness of plants used in the formulations of traditional Chinese medicine (TCM), which were also used in clinical trials to treat patients with the novel coronavirus COVID-19, and to assess their effects on the cardiovascular system. Method...
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| Format: | Article |
| Language: | English |
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KARE Publishing
2020-06-01
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| Series: | Türk Kardiyoloji Derneği Arşivi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-03374 |
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| author | Emine Akalın Miraç Ekici Zinar Alan Elif Özbir Elevli Aysenur Yaman Bucak Nuerbiye Aobuliaikemu Ali Yağız Üresin |
| author_facet | Emine Akalın Miraç Ekici Zinar Alan Elif Özbir Elevli Aysenur Yaman Bucak Nuerbiye Aobuliaikemu Ali Yağız Üresin |
| author_sort | Emine Akalın |
| collection | DOAJ |
| description | Objective: The aim of this study was to evaluate the effectiveness of plants used in the formulations of traditional Chinese medicine (TCM), which were also used in clinical trials to treat patients with the novel coronavirus COVID-19, and to assess their effects on the cardiovascular system.
Methods: A literature review of PubMed, ResearchGate, ScienceDirect, the Cochrane Library, and TCM monographs was conducted and the effects of the plants on the cardiovascular system and the mechanisms of action in COVID-19 treatment were evaluated.
Results: The mechanism of action, cardiovascular effects, and possible toxicity of 10 plants frequently found in TCM formulations that were used in the clinical treatment of COVID-19 were examined.
Conclusion: TCM formulations that had been originally developed for earlier viral diseases have been used in COVID-19 treatment. Despite the effectiveness seen in laboratory and animal studies with the most commonly used plants in these formulations, the clinical studies are currently insufficient according to standard operating procedures. More clinical studies are needed to understand the safe clinical use of traditional plants. |
| first_indexed | 2024-04-10T12:22:37Z |
| format | Article |
| id | doaj.art-d20ba693f4e24f9eade127f081411774 |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T12:22:37Z |
| publishDate | 2020-06-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-d20ba693f4e24f9eade127f0814117742023-02-15T16:15:22ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692020-06-0148441042410.5543/tkda.2020.03374TKDA-03374Traditional Chinese medicine practices used in COVID-19 (Sars-cov 2/Coronavirus-19) treatment in clinic and their effects on the cardiovascular systemEmine Akalın0Miraç Ekici1Zinar Alan2Elif Özbir Elevli3Aysenur Yaman Bucak4Nuerbiye Aobuliaikemu5Ali Yağız Üresin6Department of Pharmaceutical Botany, Istanbul University Faculty of Pharmacy, İstanbul, TurkeyDepartment of Pharmaceutical Botany, Istanbul University Faculty of Pharmacy, İstanbul, TurkeyDepartment of Pharmaceutical Botany, Istanbul University Faculty of Pharmacy, İstanbul, TurkeyDepartment of Pharmaceutical Botany, Istanbul University Faculty of Pharmacy, İstanbul, TurkeyDepartment of Medical Pharmacology, Istanbul University Faculty of Medicine, İstanbul, TurkeyDepartment of Pharmacognosy, İstanbul University Faculty of Pharmacy, İstanbul, TurkeyDepartment of Medical Pharmacology, Istanbul University Faculty of Medicine, İstanbul, TurkeyObjective: The aim of this study was to evaluate the effectiveness of plants used in the formulations of traditional Chinese medicine (TCM), which were also used in clinical trials to treat patients with the novel coronavirus COVID-19, and to assess their effects on the cardiovascular system. Methods: A literature review of PubMed, ResearchGate, ScienceDirect, the Cochrane Library, and TCM monographs was conducted and the effects of the plants on the cardiovascular system and the mechanisms of action in COVID-19 treatment were evaluated. Results: The mechanism of action, cardiovascular effects, and possible toxicity of 10 plants frequently found in TCM formulations that were used in the clinical treatment of COVID-19 were examined. Conclusion: TCM formulations that had been originally developed for earlier viral diseases have been used in COVID-19 treatment. Despite the effectiveness seen in laboratory and animal studies with the most commonly used plants in these formulations, the clinical studies are currently insufficient according to standard operating procedures. More clinical studies are needed to understand the safe clinical use of traditional plants.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-03374antiviralcardiovascular system; covid-19; immunomodulator; traditional chinese medicine. |
| spellingShingle | Emine Akalın Miraç Ekici Zinar Alan Elif Özbir Elevli Aysenur Yaman Bucak Nuerbiye Aobuliaikemu Ali Yağız Üresin Traditional Chinese medicine practices used in COVID-19 (Sars-cov 2/Coronavirus-19) treatment in clinic and their effects on the cardiovascular system Türk Kardiyoloji Derneği Arşivi antiviral cardiovascular system; covid-19; immunomodulator; traditional chinese medicine. |
| title | Traditional Chinese medicine practices used in COVID-19 (Sars-cov 2/Coronavirus-19) treatment in clinic and their effects on the cardiovascular system |
| title_full | Traditional Chinese medicine practices used in COVID-19 (Sars-cov 2/Coronavirus-19) treatment in clinic and their effects on the cardiovascular system |
| title_fullStr | Traditional Chinese medicine practices used in COVID-19 (Sars-cov 2/Coronavirus-19) treatment in clinic and their effects on the cardiovascular system |
| title_full_unstemmed | Traditional Chinese medicine practices used in COVID-19 (Sars-cov 2/Coronavirus-19) treatment in clinic and their effects on the cardiovascular system |
| title_short | Traditional Chinese medicine practices used in COVID-19 (Sars-cov 2/Coronavirus-19) treatment in clinic and their effects on the cardiovascular system |
| title_sort | traditional chinese medicine practices used in covid 19 sars cov 2 coronavirus 19 treatment in clinic and their effects on the cardiovascular system |
| topic | antiviral cardiovascular system; covid-19; immunomodulator; traditional chinese medicine. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-03374 |
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