Whole slide imaging in pathology: advantages, limitations, and emerging perspectives
Navid Farahani,1 Anil V Parwani,2 Liron Pantanowitz2 1Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA; 2Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Abstract: Significant technologic gains have led to th...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2015-06-01
|
| Series: | Pathology and Laboratory Medicine International |
| Online Access: | http://www.dovepress.com/whole-slide-imaging-in-pathology-advantages-limitations-and-emerging-p-peer-reviewed-article-PLMI |
| _version_ | 1819169526187556864 |
|---|---|
| author | Farahani N Parwani AV Pantanowitz L |
| author_facet | Farahani N Parwani AV Pantanowitz L |
| author_sort | Farahani N |
| collection | DOAJ |
| description | Navid Farahani,1 Anil V Parwani,2 Liron Pantanowitz2 1Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA; 2Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Abstract: Significant technologic gains have led to the adoption of innovative digital imaging solutions in pathology. Whole slide imaging (WSI), which refers to scanning of conventional glass slides in order to produce digital slides, is the most recent imaging modality being employed by pathology departments worldwide. WSI continues to gain traction among pathologists for diagnostic, educational, and research purposes. This article provides a technologic review of WSI platforms and covers clinical and nonclinical pathology applications of these imaging systems. Barriers to adoption of WSI include limiting technology, image quality, problems with scanning all materials (eg, cytology slides), cost, digital slide storage, inability to handle high-throughput routine work, regulatory barriers, ergonomics, and pathologists' reluctance. Emerging issues related to clinical validation, standardization, and forthcoming advances in the field are also addressed. Keywords: digital, imaging, microscopy, pathology, validation, whole slide image, telepathology |
| first_indexed | 2024-12-22T19:20:54Z |
| format | Article |
| id | doaj.art-d20d3293ef7a45bd86ccea993449e66d |
| institution | Directory Open Access Journal |
| issn | 1179-2698 |
| language | English |
| last_indexed | 2024-12-22T19:20:54Z |
| publishDate | 2015-06-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Pathology and Laboratory Medicine International |
| spelling | doaj.art-d20d3293ef7a45bd86ccea993449e66d2022-12-21T18:15:23ZengDove Medical PressPathology and Laboratory Medicine International1179-26982015-06-012015default233322116Whole slide imaging in pathology: advantages, limitations, and emerging perspectivesFarahani NParwani AVPantanowitz LNavid Farahani,1 Anil V Parwani,2 Liron Pantanowitz2 1Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA; 2Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA Abstract: Significant technologic gains have led to the adoption of innovative digital imaging solutions in pathology. Whole slide imaging (WSI), which refers to scanning of conventional glass slides in order to produce digital slides, is the most recent imaging modality being employed by pathology departments worldwide. WSI continues to gain traction among pathologists for diagnostic, educational, and research purposes. This article provides a technologic review of WSI platforms and covers clinical and nonclinical pathology applications of these imaging systems. Barriers to adoption of WSI include limiting technology, image quality, problems with scanning all materials (eg, cytology slides), cost, digital slide storage, inability to handle high-throughput routine work, regulatory barriers, ergonomics, and pathologists' reluctance. Emerging issues related to clinical validation, standardization, and forthcoming advances in the field are also addressed. Keywords: digital, imaging, microscopy, pathology, validation, whole slide image, telepathologyhttp://www.dovepress.com/whole-slide-imaging-in-pathology-advantages-limitations-and-emerging-p-peer-reviewed-article-PLMI |
| spellingShingle | Farahani N Parwani AV Pantanowitz L Whole slide imaging in pathology: advantages, limitations, and emerging perspectives Pathology and Laboratory Medicine International |
| title | Whole slide imaging in pathology: advantages, limitations, and emerging perspectives |
| title_full | Whole slide imaging in pathology: advantages, limitations, and emerging perspectives |
| title_fullStr | Whole slide imaging in pathology: advantages, limitations, and emerging perspectives |
| title_full_unstemmed | Whole slide imaging in pathology: advantages, limitations, and emerging perspectives |
| title_short | Whole slide imaging in pathology: advantages, limitations, and emerging perspectives |
| title_sort | whole slide imaging in pathology advantages limitations and emerging perspectives |
| url | http://www.dovepress.com/whole-slide-imaging-in-pathology-advantages-limitations-and-emerging-p-peer-reviewed-article-PLMI |
| work_keys_str_mv | AT farahanin wholeslideimaginginpathologyadvantageslimitationsandemergingperspectives AT parwaniav wholeslideimaginginpathologyadvantageslimitationsandemergingperspectives AT pantanowitzl wholeslideimaginginpathologyadvantageslimitationsandemergingperspectives |