An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation
Introduction: The International Society for Sexual Medicine (ISSM) Ad Hoc Committee for the Definition of Premature Ejaculation developed the first evidence-based definition for lifelong premature ejaculation (PE) in 2007 and concluded that there were insufficient published objective data at that ti...
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| Format: | Article |
| Language: | English |
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Oxford University Press
2014-06-01
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| Series: | Sexual Medicine |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2050116115300325 |
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| author | Ege Can Serefoglu, MD Chris G. McMahon, MD Marcel D. Waldinger, MD, PhD Stanley E. Althof, PhD Alan Shindel, MD Ganesh Adaikan, PhD Edgardo F. Becher, MD John Dean, MD Francois Giuliano, MD, PhD Wayne J.G. Hellstrom, MD Annamaria Giraldi, MD, PhD Sidney Glina, MD, PhD Luca Incrocci, MD, PhD Emmanuele Jannini, MD Marita McCabe, PhD Sharon Parish, MD David Rowland, PhD R. Taylor Segraves, MD, PhD Ira Sharlip, MD Luiz Otavio Torres, MD |
| author_facet | Ege Can Serefoglu, MD Chris G. McMahon, MD Marcel D. Waldinger, MD, PhD Stanley E. Althof, PhD Alan Shindel, MD Ganesh Adaikan, PhD Edgardo F. Becher, MD John Dean, MD Francois Giuliano, MD, PhD Wayne J.G. Hellstrom, MD Annamaria Giraldi, MD, PhD Sidney Glina, MD, PhD Luca Incrocci, MD, PhD Emmanuele Jannini, MD Marita McCabe, PhD Sharon Parish, MD David Rowland, PhD R. Taylor Segraves, MD, PhD Ira Sharlip, MD Luiz Otavio Torres, MD |
| author_sort | Ege Can Serefoglu, MD |
| collection | DOAJ |
| description | Introduction: The International Society for Sexual Medicine (ISSM) Ad Hoc Committee for the Definition of Premature Ejaculation developed the first evidence-based definition for lifelong premature ejaculation (PE) in 2007 and concluded that there were insufficient published objective data at that time to develop a definition for acquired PE.
Aim: The aim of this article is to review and critique the current literature and develop a contemporary, evidence-based definition for acquired PE and/or a unified definition for both lifelong and acquired PE.
Methods: In April 2013, the ISSM convened a second Ad Hoc Committee for the Definition of Premature Ejaculation in Bangalore, India. The same evidence-based systematic approach to literature search, retrieval, and evaluation used by the original committee was adopted.
Results: The committee unanimously agreed that men with lifelong and acquired PE appear to share the dimensions of short ejaculatory latency, reduced or absent perceived ejaculatory control, and the presence of negative personal consequences. Men with acquired PE are older, have higher incidences of erectile dysfunction, comorbid disease, and cardiovascular risk factors, and have a longer intravaginal ejaculation latency time (IELT) as compared with men with lifelong PE. A self-estimated or stopwatch IELT of 3 minutes was identified as a valid IELT cut-off for diagnosing acquired PE. On this basis, the committee agreed on a unified definition of both acquired and lifelong PE as a male sexual dysfunction characterized by (i) ejaculation that always or nearly always occurs prior to or within about 1 minute of vaginal penetration from the first sexual experience (lifelong PE) or a clinically significant and bothersome reduction in latency time, often to about 3 minutes or less (acquired PE); (ii) the inability to delay ejaculation on all or nearly all vaginal penetrations; and (iii) negative personal consequences, such as distress, bother, frustration, and/or the avoidance of sexual intimacy.
Conclusion: The ISSM unified definition of lifelong and acquired PE represents the first evidence-based definition for these conditions. This definition will enable researchers to design methodologically rigorous studies to improve our understanding of acquired PE. Serefoglu EC, McMahon CG, Waldinger MD, Althof SE, Shindel A, Adaikan G, Becher EF, Dean J, Giuliano F, Hellstrom WJG, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, and Torres LO. An evidence-based unified definition of lifelong and acquired premature ejaculation: Report of the second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation. Sex Med 2014;2:41–59. |
| first_indexed | 2024-03-12T09:47:34Z |
| format | Article |
| id | doaj.art-d20fc83b312d428797e1bbe3ed785a58 |
| institution | Directory Open Access Journal |
| issn | 2050-1161 |
| language | English |
| last_indexed | 2024-03-12T09:47:34Z |
| publishDate | 2014-06-01 |
| publisher | Oxford University Press |
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| series | Sexual Medicine |
| spelling | doaj.art-d20fc83b312d428797e1bbe3ed785a582023-09-02T12:47:25ZengOxford University PressSexual Medicine2050-11612014-06-0122415910.1002/sm2.27An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature EjaculationEge Can Serefoglu, MD0Chris G. McMahon, MD1Marcel D. Waldinger, MD, PhD2Stanley E. Althof, PhD3Alan Shindel, MD4Ganesh Adaikan, PhD5Edgardo F. Becher, MD6John Dean, MD7Francois Giuliano, MD, PhD8Wayne J.G. Hellstrom, MD9Annamaria Giraldi, MD, PhD10Sidney Glina, MD, PhD11Luca Incrocci, MD, PhD12Emmanuele Jannini, MD13Marita McCabe, PhD14Sharon Parish, MD15David Rowland, PhD16R. Taylor Segraves, MD, PhD17Ira Sharlip, MD18Luiz Otavio Torres, MD19Department of Urology, Bagcilar Training & Research Hospital, Istanbul, TurkeyAustralian Center for Sexual Health, Sydney, New South Wales, AustraliaDepartment of Pharmacology, Utrecht Institute of Pharmaceutical Sciences, University of Utrecht, Utrecht, The NetherlandsDepartment of Psychiatry, Case Western Reserve University School of Medicine, West Palm Beach, FL, USADepartment of Urology, University of California at Davis, Davis, CA, USADepartment of Obstetrics and Gynecology, National University of Singapore, SingaporeDivision of Urology, University of Buenos Aires, Buenos Aires, ArgentinaSt. Peter's Sexual Medicine Centre, The London Clinic, London, UKNeuro-Uro-Andrology Unit, Physical Medicine and Rehabilitation Department, Raymond Poincaré Hospital, Paris, FranceDepartment of Urology, Tulane University Health Sciences Center, New Orleans, LA, USADepartment of Sexological Research, Psychiatric Center Copenhagen, Rigshospitalet, Copenhagen, DenmarkDepartment of Urology, Instituto H. Ellis, Sao Paulo, BrazilErasmus MC–Daniel den Hoed Cancer Center, Rotterdam, The NetherlandsEndocrinology and Medical Sexology, Department of Experimental Medicine, University of L'AquilaL'Aquila, ItalySchool of Psychology, Deakin University, Melbourne, Victoria, AustraliaMontefiore Medical Center, Department of Medicine, Albert Einstein College of Medicine, New York, NY, USAGraduate School, Valparaiso University, Valparaiso, IN, USADepartment of PsychiatryCase Western Reserve University School of Medicine, Cleveland, OH, USADepartment of Urology, University of CaliforniaSan Francisco, CA, USAClinica de Urologia e Andrologia, Belo Horizonte, Minas Gerais, BrazilIntroduction: The International Society for Sexual Medicine (ISSM) Ad Hoc Committee for the Definition of Premature Ejaculation developed the first evidence-based definition for lifelong premature ejaculation (PE) in 2007 and concluded that there were insufficient published objective data at that time to develop a definition for acquired PE. Aim: The aim of this article is to review and critique the current literature and develop a contemporary, evidence-based definition for acquired PE and/or a unified definition for both lifelong and acquired PE. Methods: In April 2013, the ISSM convened a second Ad Hoc Committee for the Definition of Premature Ejaculation in Bangalore, India. The same evidence-based systematic approach to literature search, retrieval, and evaluation used by the original committee was adopted. Results: The committee unanimously agreed that men with lifelong and acquired PE appear to share the dimensions of short ejaculatory latency, reduced or absent perceived ejaculatory control, and the presence of negative personal consequences. Men with acquired PE are older, have higher incidences of erectile dysfunction, comorbid disease, and cardiovascular risk factors, and have a longer intravaginal ejaculation latency time (IELT) as compared with men with lifelong PE. A self-estimated or stopwatch IELT of 3 minutes was identified as a valid IELT cut-off for diagnosing acquired PE. On this basis, the committee agreed on a unified definition of both acquired and lifelong PE as a male sexual dysfunction characterized by (i) ejaculation that always or nearly always occurs prior to or within about 1 minute of vaginal penetration from the first sexual experience (lifelong PE) or a clinically significant and bothersome reduction in latency time, often to about 3 minutes or less (acquired PE); (ii) the inability to delay ejaculation on all or nearly all vaginal penetrations; and (iii) negative personal consequences, such as distress, bother, frustration, and/or the avoidance of sexual intimacy. Conclusion: The ISSM unified definition of lifelong and acquired PE represents the first evidence-based definition for these conditions. This definition will enable researchers to design methodologically rigorous studies to improve our understanding of acquired PE. Serefoglu EC, McMahon CG, Waldinger MD, Althof SE, Shindel A, Adaikan G, Becher EF, Dean J, Giuliano F, Hellstrom WJG, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, and Torres LO. An evidence-based unified definition of lifelong and acquired premature ejaculation: Report of the second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation. Sex Med 2014;2:41–59.http://www.sciencedirect.com/science/article/pii/S2050116115300325Premature EjaculationDefinitionLifelong Premature EjaculationAcquired Premature EjaculationIntravaginal Ejaculatory Latency TimeEjaculatory ControlSexual SatisfactionPersonal DistressInterpersonal DistressNegative Personal Psychological Consequences |
| spellingShingle | Ege Can Serefoglu, MD Chris G. McMahon, MD Marcel D. Waldinger, MD, PhD Stanley E. Althof, PhD Alan Shindel, MD Ganesh Adaikan, PhD Edgardo F. Becher, MD John Dean, MD Francois Giuliano, MD, PhD Wayne J.G. Hellstrom, MD Annamaria Giraldi, MD, PhD Sidney Glina, MD, PhD Luca Incrocci, MD, PhD Emmanuele Jannini, MD Marita McCabe, PhD Sharon Parish, MD David Rowland, PhD R. Taylor Segraves, MD, PhD Ira Sharlip, MD Luiz Otavio Torres, MD An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation Sexual Medicine Premature Ejaculation Definition Lifelong Premature Ejaculation Acquired Premature Ejaculation Intravaginal Ejaculatory Latency Time Ejaculatory Control Sexual Satisfaction Personal Distress Interpersonal Distress Negative Personal Psychological Consequences |
| title | An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation |
| title_full | An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation |
| title_fullStr | An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation |
| title_full_unstemmed | An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation |
| title_short | An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation |
| title_sort | evidence based unified definition of lifelong and acquired premature ejaculation report of the second international society for sexual medicine ad hoc committee for the definition of premature ejaculation |
| topic | Premature Ejaculation Definition Lifelong Premature Ejaculation Acquired Premature Ejaculation Intravaginal Ejaculatory Latency Time Ejaculatory Control Sexual Satisfaction Personal Distress Interpersonal Distress Negative Personal Psychological Consequences |
| url | http://www.sciencedirect.com/science/article/pii/S2050116115300325 |
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