Evaluation of fetal and maternal outcomes in chorion villus sampling (CVS)
Background: Chorionic villus sampling (CVS) is one of the invasive diagnostic methods used to diagnose chromosomal, genetic, and metabolic diseases in the embryonic period. The use of this method is associated with maternal and fetal consequences, the most serious of which is abortion. Therefore, th...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Advanced Biomedical Research |
| Subjects: | |
| Online Access: | http://www.advbiores.net/article.asp?issn=2277-9175;year=2023;volume=12;issue=1;spage=133;epage=133;aulast=Movahedi |
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| author | Minoo Movahedi Farinaz Farahbod Elahe Zarean Maryam Hajihashemi Fedyeh Haghollahi Mehri Farahmand |
| author_facet | Minoo Movahedi Farinaz Farahbod Elahe Zarean Maryam Hajihashemi Fedyeh Haghollahi Mehri Farahmand |
| author_sort | Minoo Movahedi |
| collection | DOAJ |
| description | Background: Chorionic villus sampling (CVS) is one of the invasive diagnostic methods used to diagnose chromosomal, genetic, and metabolic diseases in the embryonic period. The use of this method is associated with maternal and fetal consequences, the most serious of which is abortion. Therefore, the present study was conducted to investigate the incidence of these consequences and the factors affecting the incidence of abortion.
Materials and Methods: A cross-sectional study was performed on 98 pregnant women with CVS indications. Maternal and fetal outcomes including abortion, vaginal bleeding, subchorionic hematoma, premature rupture of membrane (PROM), chorioamnionitis, preterm delivery, limb abnormality, fetal growth retardation, and preeclampsia were recorded.
Results: The results of the present study showed that the incidence of fetal outcomes including fetal growth failure, premature rupture of membranes, abortion, and limb abnormalities was 4.1%, 7.1%, 3.1%, and 1%, and the incidence of maternal outcomes including preterm delivery, subchorionic hematoma, preeclampsia, and hemorrhage was 14.3%, 3.1%, 6.1%, and 10.2%, respectively. In addition, a decrease in free BHCG and an increase in NT were significantly associated with the occurrence of abortion (OR: 0.11 and 4.25, respectively, P value < 0.05).
Conclusion: It should be noted that due to a long time between placental sampling and the occurrence of vaginal bleeding, premature rupture of membrane, and preterm delivery, it seems that placental sampling has no effect. In addition, only a decrease in free BHCG or an increase in NT significantly increased the chance of miscarriage. |
| first_indexed | 2024-03-11T15:48:25Z |
| format | Article |
| id | doaj.art-d2106b439ca44400b9680d02e93f69d6 |
| institution | Directory Open Access Journal |
| issn | 2277-9175 |
| language | English |
| last_indexed | 2024-03-11T15:48:25Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Advanced Biomedical Research |
| spelling | doaj.art-d2106b439ca44400b9680d02e93f69d62023-10-26T05:43:17ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752023-01-0112113313310.4103/abr.abr_229_22Evaluation of fetal and maternal outcomes in chorion villus sampling (CVS)Minoo MovahediFarinaz FarahbodElahe ZareanMaryam HajihashemiFedyeh HaghollahiMehri FarahmandBackground: Chorionic villus sampling (CVS) is one of the invasive diagnostic methods used to diagnose chromosomal, genetic, and metabolic diseases in the embryonic period. The use of this method is associated with maternal and fetal consequences, the most serious of which is abortion. Therefore, the present study was conducted to investigate the incidence of these consequences and the factors affecting the incidence of abortion. Materials and Methods: A cross-sectional study was performed on 98 pregnant women with CVS indications. Maternal and fetal outcomes including abortion, vaginal bleeding, subchorionic hematoma, premature rupture of membrane (PROM), chorioamnionitis, preterm delivery, limb abnormality, fetal growth retardation, and preeclampsia were recorded. Results: The results of the present study showed that the incidence of fetal outcomes including fetal growth failure, premature rupture of membranes, abortion, and limb abnormalities was 4.1%, 7.1%, 3.1%, and 1%, and the incidence of maternal outcomes including preterm delivery, subchorionic hematoma, preeclampsia, and hemorrhage was 14.3%, 3.1%, 6.1%, and 10.2%, respectively. In addition, a decrease in free BHCG and an increase in NT were significantly associated with the occurrence of abortion (OR: 0.11 and 4.25, respectively, P value < 0.05). Conclusion: It should be noted that due to a long time between placental sampling and the occurrence of vaginal bleeding, premature rupture of membrane, and preterm delivery, it seems that placental sampling has no effect. In addition, only a decrease in free BHCG or an increase in NT significantly increased the chance of miscarriage.http://www.advbiores.net/article.asp?issn=2277-9175;year=2023;volume=12;issue=1;spage=133;epage=133;aulast=Movahediabortionchorionic villus samplingchromosomal abnormalitiespreeclampsiapregnancy outcome |
| spellingShingle | Minoo Movahedi Farinaz Farahbod Elahe Zarean Maryam Hajihashemi Fedyeh Haghollahi Mehri Farahmand Evaluation of fetal and maternal outcomes in chorion villus sampling (CVS) Advanced Biomedical Research abortion chorionic villus sampling chromosomal abnormalities preeclampsia pregnancy outcome |
| title | Evaluation of fetal and maternal outcomes in chorion villus sampling (CVS) |
| title_full | Evaluation of fetal and maternal outcomes in chorion villus sampling (CVS) |
| title_fullStr | Evaluation of fetal and maternal outcomes in chorion villus sampling (CVS) |
| title_full_unstemmed | Evaluation of fetal and maternal outcomes in chorion villus sampling (CVS) |
| title_short | Evaluation of fetal and maternal outcomes in chorion villus sampling (CVS) |
| title_sort | evaluation of fetal and maternal outcomes in chorion villus sampling cvs |
| topic | abortion chorionic villus sampling chromosomal abnormalities preeclampsia pregnancy outcome |
| url | http://www.advbiores.net/article.asp?issn=2277-9175;year=2023;volume=12;issue=1;spage=133;epage=133;aulast=Movahedi |
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