1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis

Asymmetric catalysis represents a very powerful tool for the synthesis of enantiopure compounds. In this context the main focus has been directed not only to the search for new efficient chiral catalysts, but also to the development of efficient pronucleophiles. This review highlights the utility an...

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Main Authors: Antonia Mielgo, Claudio Palomo
Format: Article
Language:English
Published: Beilstein-Institut 2016-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.12.90
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author Antonia Mielgo
Claudio Palomo
author_facet Antonia Mielgo
Claudio Palomo
author_sort Antonia Mielgo
collection DOAJ
description Asymmetric catalysis represents a very powerful tool for the synthesis of enantiopure compounds. In this context the main focus has been directed not only to the search for new efficient chiral catalysts, but also to the development of efficient pronucleophiles. This review highlights the utility and first examples of 1H-imidazol-4(5H)-ones and thiazol-4(5H)-ones as pronucleophiles in catalytic asymmetric reactions.
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spelling doaj.art-d2135fe6d0654be0bb2a69461e0167412022-12-21T23:04:54ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972016-05-0112191893610.3762/bjoc.12.901860-5397-12-901H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysisAntonia Mielgo0Claudio Palomo1Departamento de Química Orgánica I, Facultad de Química, Universidad del País Vasco, Apdo. 1072, 20080 San Sebastián, SpainDepartamento de Química Orgánica I, Facultad de Química, Universidad del País Vasco, Apdo. 1072, 20080 San Sebastián, SpainAsymmetric catalysis represents a very powerful tool for the synthesis of enantiopure compounds. In this context the main focus has been directed not only to the search for new efficient chiral catalysts, but also to the development of efficient pronucleophiles. This review highlights the utility and first examples of 1H-imidazol-4(5H)-ones and thiazol-4(5H)-ones as pronucleophiles in catalytic asymmetric reactions.https://doi.org/10.3762/bjoc.12.90asymmetric catalysisbifunctional catalysts1H-imidazol-4(5H)-onespronucleophilesthiazol-4(5H)-ones
spellingShingle Antonia Mielgo
Claudio Palomo
1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis
Beilstein Journal of Organic Chemistry
asymmetric catalysis
bifunctional catalysts
1H-imidazol-4(5H)-ones
pronucleophiles
thiazol-4(5H)-ones
title 1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis
title_full 1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis
title_fullStr 1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis
title_full_unstemmed 1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis
title_short 1H-Imidazol-4(5H)-ones and thiazol-4(5H)-ones as emerging pronucleophiles in asymmetric catalysis
title_sort 1h imidazol 4 5h ones and thiazol 4 5h ones as emerging pronucleophiles in asymmetric catalysis
topic asymmetric catalysis
bifunctional catalysts
1H-imidazol-4(5H)-ones
pronucleophiles
thiazol-4(5H)-ones
url https://doi.org/10.3762/bjoc.12.90
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