Acute Effects of Drugs on Caenorhabditis elegans Movement Reveal Complex Responses and Plasticity

Acute Effects of Drugs on Caenorhabditis elegans Movement Reveal Complex Responses and Plasticity

Many drugs act very rapidly — they can turn on or off their targets within minutes in a whole animal. What are the acute effects of drug treatment and how does an animal respond to these? We developed a simple assay to measure the acute effects of drugs on C. elegans movement and examined the effect...

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Bibliographic Details
Main Authors: Mark Spensley, Samantha Del Borrello, Djina Pajkic, Andrew G. Fraser
Format: Article
Language:English
Published: Oxford University Press 2018-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
C. elegans
Drug Assay
Movement
Acute Response
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.200374

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