Discrepancy between the Actions of Glucagon-like Peptide-1 Receptor Ligands in the Protection of the Heart against Ischemia Reperfusion Injury

Discrepancy between the Actions of Glucagon-like Peptide-1 Receptor Ligands in the Protection of the Heart against Ischemia Reperfusion Injury

Tirzepatide is a dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist and a promising therapy for type 2 diabetes mellitus (T2DM). GLP-1 is an incretin hormone with therapeutic potential beyond type 2 diabetes mellitus. However, GLP-1 is rapidl...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Ali Ismaeil, Fawzi Babiker, Suleiman Al-Sabah
Format:	Article
Sprog:	English
Udgivet:	MDPI AG 2022-06-01
Serier:	Pharmaceuticals
Fag:	ischemia reperfusion GLP-1 GLP-1 (9-36) exendin-4
Online adgang:	https://www.mdpi.com/1424-8247/15/6/720

Lignende værker

Liraglutide and GLP-1(9–37) alleviated hepatic ischemia-reperfusion injury by inhibiting ferroptosis via GSK3β/Nrf2 pathway and SMAD159/Hepcidin/FTH pathway
af: Chenqi Lu, et al.
Udgivet: (2025-02-01)

Exploring the Putative Involvement of MALAT1 in Mediating the Beneficial Effect of Exendin-4 on Oleic Acid-Induced Lipid Accumulation in HepG2 Cells
af: Olfa Khalifa, et al.
Udgivet: (2025-02-01)

Hepatic function of glucagon-like peptide-1 and its based diabetes drugs
af: Feng Jia Nuo, et al.
Udgivet: (2024-08-01)

Glucagon‐like peptide agonists: A prospective review
af: Zamara Mariam, et al.
Udgivet: (2024-01-01)

Out of stock: A brief clinical reference for rough equivalency of glucagon‐like peptide‐1 (GLP‐1) ± glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists for A1c and weight reduction in people with type 2 diabetes
af: Leigh Perreault, et al.
Udgivet: (2024-06-01)

Radiation-induced oxidative injury of the ileum and colon is alleviated by glucagon-like peptide-1 and -2
af: Mustafa Deniz, et al.
Udgivet: (2015-04-01)

Bolus Injection of Liraglutide Raises Plasma Glucose in Normal Rats by Activating Glucagon-like Peptide 1 Receptor in the Brain
af: Chia-Chen Hsu, et al.
Udgivet: (2022-07-01)

Glucagon and exenatide improve contractile recovery following ischaemia/reperfusion in the isolated perfused rat heart
af: Ross T. Lindsay, et al.
Udgivet: (2023-03-01)

Revolutionizing disease treatment through bioengineered probiotics and glucagon‐like peptide 1 (GLP‐1) based strategies: A path towards effective cures
af: Smriti Jain, et al.
Udgivet: (2024-09-01)

Comparison of Exendin-4 and Its Single Amino Acid Substitutions as Parent Peptides for GLP-1 Receptor Imaging Probes
af: Naoya Kondo, et al.
Udgivet: (2025-02-01)

18F-labeled PEGylated exendin-4 imaging noninvasively differentiates insulinoma from an accessory spleen: the first case report of [18F]FB(ePEG12)12-exendin-4 positron emission tomography/computed tomography for insulinoma
af: Kentaro Sakaki, et al.
Udgivet: (2023-08-01)

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may reduce the risk of developing cancer-related lymphedema following axillary lymph node dissection (ALND)
af: Stav Brown, et al.
Udgivet: (2024-09-01)

Serum Ghrelin and Glucagon-like Peptide 1 Levels in Children with Prader-Willi and Bardet-Biedl Syndromes
af: Doğa Türkkahraman, et al.
Udgivet: (2024-06-01)

Glucagon-like peptide-1 receptor agonists and derivatives in the treatment of obesity - review
af: Michal Rabenda, et al.
Udgivet: (2024-08-01)

Exendin-4 increases the firing activity of hippocampal CA1 neurons through TRPC4/5 channels
af: Hui-Zhe Sun, et al.
Udgivet: (2024-02-01)

Comparative Transcriptome Analysis Reveals That Exendin-4 Improves Steatosis in HepG2 Cells by Modulating Signaling Pathways Related to Lipid Metabolism
af: Khaoula Errafii, et al.
Udgivet: (2022-04-01)

The Impact of Glucagon-like Peptide 1 Receptor Agonists on Obstructive Sleep Apnoea: A Scoping Review
af: Khang Duy Ricky Le, et al.
Udgivet: (2024-01-01)

A Review and Meta-Analysis of the Safety and Efficacy of Using Glucagon-like Peptide-1 Receptor Agonists
af: En-Hao Hu, et al.
Udgivet: (2024-02-01)

IUPHAR review – Glucagon-like peptide-1 (GLP-1) and substance use disorders: An emerging pharmacotherapeutic target
af: Nicolaus Bruns VI, et al.
Udgivet: (2024-09-01)

Glucagon-like peptide-1 receptor agonists in neoplastic diseases
af: Lisan Ji, et al.
Udgivet: (2024-09-01)

Immunohistochemical Study on Glucagon-Like Peptide-1(GLP-1) and Pituitary Adenylate Cyclase Activating Peptide (PACAP) in the Small Intestine of Muscovy Duck during the Prehatching and Posthatching Periods
af: Baoan Ding, et al.
Udgivet: (2014-01-01)

Physiology and pharmacology of glucagon-like peptide-1 receptor
af: D. V. Kurkin, et al.
Udgivet: (2024-01-01)

Glucagon-like peptide-1 receptor agonists in patients treated with antipsychotics
af: A. Delgado, et al.
Udgivet: (2021-04-01)

Utilization of glucagon-like peptide-1 receptor agonists in children and adolescents in China: a real-world study
af: Yilong Yan, et al.
Udgivet: (2023-06-01)

The Effects of Glucagon‐Like Peptide‐1 Receptor Agonists on Mitochondrial Function Within Skeletal Muscle: A Systematic Review
af: Victoria J. Old, et al.
Udgivet: (2025-02-01)

Usage of Glucagon-Like Peptide-1 for Obesity in Children; Updated Review of Clinicaltrials.gov
af: Alorfi NM, et al.
Udgivet: (2023-07-01)

Diabetes drugs activate neuroprotective pathways in models of neonatal hypoxic-ischemic encephalopathy
af: Laura Poupon-Bejuit, et al.
Udgivet: (2024-05-01)

Brain Imaging of the GLP-1 Receptor in Obesity Using <sup>68</sup>Ga-NODAGA-Exendin-4 PET
af: Laura N. Deden, et al.
Udgivet: (2021-12-01)

Role of Glucagon‐Like Peptide‐1 Receptor Agonists in Achieving Weight Loss and Improving Cardiovascular Outcomes in People With Overweight and Obesity
af: Erin D. Michos, et al.
Udgivet: (2023-06-01)

From classical dualistic antagonism to hormone synergy: potential of overlapping action of glucagon, insulin and GLP-1 for the treatment of diabesity
af: Svjatoslavs Kistkins, et al.
Udgivet: (2024-05-01)

Mechanisms of action and therapeutic applications of GLP-1 and dual GIP/GLP-1 receptor agonists
af: Qiyuan Keith Liu
Udgivet: (2024-07-01)

Equine glucagon-like peptide-1 receptor physiology
af: Murad H. Kheder, et al.
Udgivet: (2018-01-01)

Effect of GLP-1 Receptor Agonist on Ischemia Reperfusion Injury in Rats with Metabolic Syndrome
af: Marko Ravic, et al.
Udgivet: (2024-04-01)

Compounded glucagon-like peptide-1 receptor agonists for weight loss: the direct-to-consumer market in Colorado
af: Michael J. DiStefano, et al.
Udgivet: (2025-12-01)

Glucagon-like Peptide-1 Receptor Agonists—A Potential New Medication for Pediatric Metabolic-Dysfunction-Associated Steatotic Liver Disease (MASLD)
af: Erika Choi, et al.
Udgivet: (2024-02-01)

The Interaction of Food Allergy and Diabetes: Food Allergy Effects on Diabetic Mice by Intestinal Barrier Destruction and Glucagon-like Peptide 1 Reduction in Jejunum
af: Yanjun Gu, et al.
Udgivet: (2022-11-01)

The role of human glucagon-like peptide-1 analog in therapy of type 2 dianetes mellitus
af: Marina Vladimirovna Shestakova
Udgivet: (2010-09-01)

The risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon like peptide-1 receptor agonist therapy
af: Edy Kornelius, et al.
Udgivet: (2024-10-01)

Ｅｘｅｎｄｉｎ－４对苯肾上腺素诱导的心肌肥厚的影响及作用机制
Udgivet: (2016-01-01)

Excessive accumulation of epicardial adipose tissue promotes microvascular obstruction formation after myocardial ischemia/reperfusion through modulating macrophages polarization
af: Jinxuan Zhao, et al.
Udgivet: (2024-07-01)