Sequential Hypertonic-Hypotonic Treatment Enhances Efficacy of Antibiotic against <i>Acinetobacter baumannii</i> Biofilm Communities

Sequential Hypertonic-Hypotonic Treatment Enhances Efficacy of Antibiotic against <i>Acinetobacter baumannii</i> Biofilm Communities

Infections with bacterial biofilm communities are highly tolerant of antibiotics. This protection is attributed, in part, to a hydrated extracellular polymeric substance (EPS) that surrounds the bacterial community and that limits antibiotic diffusion. In this study, we evaluated whether it is possi...

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Bibliographic Details
Main Authors: Azeza Falghoush, Haluk Beyenal, Douglas R. Call
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antibiotics
Subjects:
<i>Acinetobacter baumannii</i>
biofilm
osmotic compounds
lipophilicity
Online Access:https://www.mdpi.com/2079-6382/9/11/832

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