Malonate inhibits virulence gene expression in Vibrio cholerae.

We previously found that inhibition of the TCA cycle, either through mutations or chemical inhibition, increased toxT transcription in Vibrio cholerae. In this study, we found that the addition of malonate, an inhibitor of succinate dehydrogenase (SDH), decreased toxT transcription in V. cholerae, a...

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Detalhes bibliográficos
Main Authors: Yusuke Minato, Sara R Fassio, Claudia C Häse
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3652848?pdf=render