An overview of animal tissue decellularization techniques and clinical applications

There is a persistent an urgent need to solve tissue and organ donor shortage issues. Decellularized tissues represent a promising alternative to other biologic and synthetic treatments that have been developed, since they aim to retain native tissue characteristics that would help in the regenerati...

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Main Authors: Catalina Pineda-Molina, Sara María Galvis-Escobar, Juan David Molina-Sierra, Juan Pablo Ruíz-Soto, Maria Antonia Rego-Londoño
Format: Article
Language:English
Published: Politécnico Colombiano Jaime Isaza Cadavid 2024-03-01
Series:Revista Politécnica
Subjects:
Online Access:https://revistas.elpoli.edu.co/index.php/pol/article/view/2141
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author Catalina Pineda-Molina
Sara María Galvis-Escobar
Juan David Molina-Sierra
Juan Pablo Ruíz-Soto
Maria Antonia Rego-Londoño
author_facet Catalina Pineda-Molina
Sara María Galvis-Escobar
Juan David Molina-Sierra
Juan Pablo Ruíz-Soto
Maria Antonia Rego-Londoño
author_sort Catalina Pineda-Molina
collection DOAJ
description There is a persistent an urgent need to solve tissue and organ donor shortage issues. Decellularized tissues represent a promising alternative to other biologic and synthetic treatments that have been developed, since they aim to retain native tissue characteristics that would help in the regenerative processes such as prolifera-tion, cellular adhesion, and the presence of growth factors, while minimizing the chances of an unwanted host immune response. In the present review, we describe the most common methodologies for decellularization pro-cesses, as well as the clinical applications of these biomaterials.
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spelling doaj.art-d21e36d7e5554697a36350c0c2cff9c82024-04-01T23:25:41ZengPolitécnico Colombiano Jaime Isaza CadavidRevista Politécnica1900-23512256-53532024-03-012039314710.33571/rpolitec.v20n39a3An overview of animal tissue decellularization techniques and clinical applicationsCatalina Pineda-Molina0https://orcid.org/0000-0001-7710-6119Sara María Galvis-Escobar1https://orcid.org/0000-0001-5480-6884Juan David Molina-Sierra2https://orcid.org/0000-0002-6269-5448Juan Pablo Ruíz-Soto3https://orcid.org/0000-0002-8260-1744Maria Antonia Rego-Londoño4https://orcid.org/0000-0002-3366-8723Universidad CESUniversidad CESUniversidad CESUniversidad CESUniversidad CESThere is a persistent an urgent need to solve tissue and organ donor shortage issues. Decellularized tissues represent a promising alternative to other biologic and synthetic treatments that have been developed, since they aim to retain native tissue characteristics that would help in the regenerative processes such as prolifera-tion, cellular adhesion, and the presence of growth factors, while minimizing the chances of an unwanted host immune response. In the present review, we describe the most common methodologies for decellularization pro-cesses, as well as the clinical applications of these biomaterials.https://revistas.elpoli.edu.co/index.php/pol/article/view/2141proceso de descellularizaciónmatriz extracelulartejidodetergenteaplicaciones clínicas
spellingShingle Catalina Pineda-Molina
Sara María Galvis-Escobar
Juan David Molina-Sierra
Juan Pablo Ruíz-Soto
Maria Antonia Rego-Londoño
An overview of animal tissue decellularization techniques and clinical applications
Revista Politécnica
proceso de descellularización
matriz extracelular
tejido
detergente
aplicaciones clínicas
title An overview of animal tissue decellularization techniques and clinical applications
title_full An overview of animal tissue decellularization techniques and clinical applications
title_fullStr An overview of animal tissue decellularization techniques and clinical applications
title_full_unstemmed An overview of animal tissue decellularization techniques and clinical applications
title_short An overview of animal tissue decellularization techniques and clinical applications
title_sort overview of animal tissue decellularization techniques and clinical applications
topic proceso de descellularización
matriz extracelular
tejido
detergente
aplicaciones clínicas
url https://revistas.elpoli.edu.co/index.php/pol/article/view/2141
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