Radiofrequency versus Ethanol Ablation for Single-Session Treatment of Benign Cystic Thyroid Nodules: A Short-Term Retrospective Study
Van Bang Nguyen,1,* Xuan Nguyen Thi,1 Hau Nguyen Van Vy,1 Tuyen Linh Pham Nguyen,1 Thuy Nguyen Hai,2 Nguyen Dinh Toan,2 Chi Van Le2,* 1Center of Endocrinology and Diabetes, Family Hospital, Da Nang, Vietnam; 2Department of Internal Medicine, Hue University of Medicine and Pharmacy, H...
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| Format: | Article |
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Dove Medical Press
2023-01-01
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| Series: | Therapeutics and Clinical Risk Management |
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| Online Access: | https://www.dovepress.com/radiofrequency-versus-ethanol-ablation-for-single-session-treatment-of-peer-reviewed-fulltext-article-TCRM |
| _version_ | 1828055726873903104 |
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| author | Nguyen VB Nguyen Thi X Nguyen Van Vy H Pham Nguyen TL Nguyen Hai T Dinh Toan N Le CV |
| author_facet | Nguyen VB Nguyen Thi X Nguyen Van Vy H Pham Nguyen TL Nguyen Hai T Dinh Toan N Le CV |
| author_sort | Nguyen VB |
| collection | DOAJ |
| description | Van Bang Nguyen,1,* Xuan Nguyen Thi,1 Hau Nguyen Van Vy,1 Tuyen Linh Pham Nguyen,1 Thuy Nguyen Hai,2 Nguyen Dinh Toan,2 Chi Van Le2,* 1Center of Endocrinology and Diabetes, Family Hospital, Da Nang, Vietnam; 2Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam*These authors contributed equally to this workCorrespondence: Van Bang Nguyen, Center of Endocrinology and Diabetes, Family Hospital, No. 73 Nguyen Huu Tho Str, Da Nang, Vietnam, Tel +84 973445417, Email vanbangvnn@gmail.com Chi Van Le, Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam, Tel +84913426457, Email lvanchi@hueuni.edu.vnObjective: This study aims to compare 1-month’s efficacy and safety of single-session ethanol ablation and radiofrequency ablation for treating both purely cystic nodules and predominantly cystic thyroid nodules.Materials and methods: This short-term retrospective study was approved by the Ethics Committee of the Institutional Review Board of Danang Family hospital, and written informed consent for procedures was obtained for all patients. Thirty-nine patients who presented with cystic thyroid nodules and met inclusion criteria were extracted from the computerized medical records. The internal fluid of cystic thyroid nodules was aspirated as much as possible. Ethanol ablation was performed using 18-gauge needles with 99.5% ethanol, and RFA used a cooled-electrode RFA system and 18-gauge internally cooled electrodes via the trans-isthmic approach, moving-shot technique. Nodule volume, therapeutic success rate, the largest diameter, thyroid function tests, and complications were evaluated and compared before and after treatment in each group.Results: Among 39 patients, 17 patients were undergone EA (mean age of 47.35 years; the proportion of female of 76.5%; purely thyroid cyst percentage of 41.4%) and 22 patients were undergone RFA (mean age of 46.63 years; the proportion of female of 86.4%; purely thyroid cyst percentage of 54.5%). Both treatment techniques showed a significant reduction of the largest diameter and nodule volume (p< 0.05) without complications. RFA reduced nodule volume and the largest nodule size greater than EA treatment at 1-month post-ablation (p< 0.05). In addition, the therapeutic success rate in the RFA group was higher than in the EA group.Conclusion: Both RFA and EA treatment with single-session confirm the efficacy and safety for cystic thyroid nodules at 1-month follow-up, RFA reduced greater in nodule volume and the largest nodule size than the EA treatment. Thus, the therapeutic success rate in the RFA group was higher than in the EA group.Keywords: radiofrequency ablation, ethanol ablation, cystic thyroid nodules, efficacy and safety |
| first_indexed | 2024-04-10T20:43:04Z |
| format | Article |
| id | doaj.art-d21fb535431e4eb6948276e04ac32a9c |
| institution | Directory Open Access Journal |
| issn | 1178-203X |
| language | English |
| last_indexed | 2024-04-10T20:43:04Z |
| publishDate | 2023-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Therapeutics and Clinical Risk Management |
| spelling | doaj.art-d21fb535431e4eb6948276e04ac32a9c2023-01-24T18:10:56ZengDove Medical PressTherapeutics and Clinical Risk Management1178-203X2023-01-01Volume 199710481208Radiofrequency versus Ethanol Ablation for Single-Session Treatment of Benign Cystic Thyroid Nodules: A Short-Term Retrospective StudyNguyen VBNguyen Thi XNguyen Van Vy HPham Nguyen TLNguyen Hai TDinh Toan NLe CVVan Bang Nguyen,1,* Xuan Nguyen Thi,1 Hau Nguyen Van Vy,1 Tuyen Linh Pham Nguyen,1 Thuy Nguyen Hai,2 Nguyen Dinh Toan,2 Chi Van Le2,* 1Center of Endocrinology and Diabetes, Family Hospital, Da Nang, Vietnam; 2Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam*These authors contributed equally to this workCorrespondence: Van Bang Nguyen, Center of Endocrinology and Diabetes, Family Hospital, No. 73 Nguyen Huu Tho Str, Da Nang, Vietnam, Tel +84 973445417, Email vanbangvnn@gmail.com Chi Van Le, Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam, Tel +84913426457, Email lvanchi@hueuni.edu.vnObjective: This study aims to compare 1-month’s efficacy and safety of single-session ethanol ablation and radiofrequency ablation for treating both purely cystic nodules and predominantly cystic thyroid nodules.Materials and methods: This short-term retrospective study was approved by the Ethics Committee of the Institutional Review Board of Danang Family hospital, and written informed consent for procedures was obtained for all patients. Thirty-nine patients who presented with cystic thyroid nodules and met inclusion criteria were extracted from the computerized medical records. The internal fluid of cystic thyroid nodules was aspirated as much as possible. Ethanol ablation was performed using 18-gauge needles with 99.5% ethanol, and RFA used a cooled-electrode RFA system and 18-gauge internally cooled electrodes via the trans-isthmic approach, moving-shot technique. Nodule volume, therapeutic success rate, the largest diameter, thyroid function tests, and complications were evaluated and compared before and after treatment in each group.Results: Among 39 patients, 17 patients were undergone EA (mean age of 47.35 years; the proportion of female of 76.5%; purely thyroid cyst percentage of 41.4%) and 22 patients were undergone RFA (mean age of 46.63 years; the proportion of female of 86.4%; purely thyroid cyst percentage of 54.5%). Both treatment techniques showed a significant reduction of the largest diameter and nodule volume (p< 0.05) without complications. RFA reduced nodule volume and the largest nodule size greater than EA treatment at 1-month post-ablation (p< 0.05). In addition, the therapeutic success rate in the RFA group was higher than in the EA group.Conclusion: Both RFA and EA treatment with single-session confirm the efficacy and safety for cystic thyroid nodules at 1-month follow-up, RFA reduced greater in nodule volume and the largest nodule size than the EA treatment. Thus, the therapeutic success rate in the RFA group was higher than in the EA group.Keywords: radiofrequency ablation, ethanol ablation, cystic thyroid nodules, efficacy and safetyhttps://www.dovepress.com/radiofrequency-versus-ethanol-ablation-for-single-session-treatment-of-peer-reviewed-fulltext-article-TCRMradiofrequency ablationethanol ablationcystic thyroid nodulesefficacy and safety |
| spellingShingle | Nguyen VB Nguyen Thi X Nguyen Van Vy H Pham Nguyen TL Nguyen Hai T Dinh Toan N Le CV Radiofrequency versus Ethanol Ablation for Single-Session Treatment of Benign Cystic Thyroid Nodules: A Short-Term Retrospective Study Therapeutics and Clinical Risk Management radiofrequency ablation ethanol ablation cystic thyroid nodules efficacy and safety |
| title | Radiofrequency versus Ethanol Ablation for Single-Session Treatment of Benign Cystic Thyroid Nodules: A Short-Term Retrospective Study |
| title_full | Radiofrequency versus Ethanol Ablation for Single-Session Treatment of Benign Cystic Thyroid Nodules: A Short-Term Retrospective Study |
| title_fullStr | Radiofrequency versus Ethanol Ablation for Single-Session Treatment of Benign Cystic Thyroid Nodules: A Short-Term Retrospective Study |
| title_full_unstemmed | Radiofrequency versus Ethanol Ablation for Single-Session Treatment of Benign Cystic Thyroid Nodules: A Short-Term Retrospective Study |
| title_short | Radiofrequency versus Ethanol Ablation for Single-Session Treatment of Benign Cystic Thyroid Nodules: A Short-Term Retrospective Study |
| title_sort | radiofrequency versus ethanol ablation for single session treatment of benign cystic thyroid nodules a short term retrospective study |
| topic | radiofrequency ablation ethanol ablation cystic thyroid nodules efficacy and safety |
| url | https://www.dovepress.com/radiofrequency-versus-ethanol-ablation-for-single-session-treatment-of-peer-reviewed-fulltext-article-TCRM |
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