Severe adenovirus infection outbreak in Colombia: Experience from a tertiary pediatric hospital in 2022
Introduction. During the SARS-CoV-2 pandemic, many countries experienced decreased respiratory virus circulation, followed by an out-of-season outbreak. In a pediatric hospital in Colombia, we observed a surge in severe adenovirus infections, leading to concerns about the impact of eased public heal...
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| Format: | Article |
| Language: | English |
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Instituto Nacional de Salud
2024-03-01
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| Series: | Biomédica: revista del Instituto Nacional de Salud |
| Subjects: | |
| Online Access: | https://revistabiomedica.org/index.php/biomedica/article/view/7047 |
| _version_ | 1797197630360518656 |
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| author | Natalia Vélez-Tirado Lina Castaño-Jaramillo Sonia Restrepo-Gualteros Catalina Alcalá-Lozano Erika Ruge Carolina Puente Diana Li-Zeng Diego Chaparro-Arce María Camila Beltrán-Dimas Juan Francisco López Miguel Luengas-Monroy Diego Galvis-Trujillo Iván Gutiérrez-Tobar Pablo Vásquez-Hoyos Germán Camacho-Moreno |
| author_facet | Natalia Vélez-Tirado Lina Castaño-Jaramillo Sonia Restrepo-Gualteros Catalina Alcalá-Lozano Erika Ruge Carolina Puente Diana Li-Zeng Diego Chaparro-Arce María Camila Beltrán-Dimas Juan Francisco López Miguel Luengas-Monroy Diego Galvis-Trujillo Iván Gutiérrez-Tobar Pablo Vásquez-Hoyos Germán Camacho-Moreno |
| author_sort | Natalia Vélez-Tirado |
| collection | DOAJ |
| description | Introduction. During the SARS-CoV-2 pandemic, many countries experienced decreased respiratory virus circulation, followed by an out-of-season outbreak. In a pediatric hospital in Colombia, we observed a surge in severe adenovirus infections, leading to concerns about the impact of eased public health restrictions and immune debt in children under five years old.
Objective. To describe the clinical characteristics of patients with severe adenovirus infection in a pediatric hospital in Colombia.
Materials and methods. We reviewed the data of 227 patients with severe adenovirus infection at the Fundación Hospital Pediátrico La Misericordia.
Results. A total of 196 patients were included in this study. The median age was two years, and 62% were male. Adenoviruses were isolated from all patients’ samples. Ninetyseven percent were admitted to the pediatric intensive care unit, 94% required respiratory support, and the in-hospital lethality rate was 11%.
Conclusion. In 2022, there was an outbreak of severe adenovirus infections, affecting mainly children under five years of age, with higher-than-usual mortality. |
| first_indexed | 2024-04-24T06:47:01Z |
| format | Article |
| id | doaj.art-d2205c8485a2426785f4e8ec72ef188d |
| institution | Directory Open Access Journal |
| issn | 0120-4157 2590-7379 |
| language | English |
| last_indexed | 2024-04-24T06:47:01Z |
| publishDate | 2024-03-01 |
| publisher | Instituto Nacional de Salud |
| record_format | Article |
| series | Biomédica: revista del Instituto Nacional de Salud |
| spelling | doaj.art-d2205c8485a2426785f4e8ec72ef188d2024-04-22T17:48:05ZengInstituto Nacional de SaludBiomédica: revista del Instituto Nacional de Salud0120-41572590-73792024-03-0144110811210.7705/biomedica.70478502Severe adenovirus infection outbreak in Colombia: Experience from a tertiary pediatric hospital in 2022Natalia Vélez-Tirado0https://orcid.org/0000-0002-2936-3679Lina Castaño-Jaramillo1https://orcid.org/0000-0003-1478-8401Sonia Restrepo-Gualteros2https://orcid.org/0000-0003-3870-4102Catalina Alcalá-Lozano3https://orcid.org/0000-0002-8964-486XErika Ruge4https://orcid.org/0009-0006-0142-0519Carolina Puente5Diana Li-Zeng6https://orcid.org/0000-0001-8562-4960Diego Chaparro-Arce7https://orcid.org/0000-0002-1064-9191María Camila Beltrán-Dimas8Juan Francisco López9https://orcid.org/0000-0003-3175-1651Miguel Luengas-Monroy10https://orcid.org/0000-0002-3715-3137Diego Galvis-Trujillo11https://orcid.org/0000-0002-1359-2311Iván Gutiérrez-Tobar12Pablo Vásquez-Hoyos13https://orcid.org/0000-0002-4892-5032Germán Camacho-Moreno14https://orcid.org/0000-0003-0472-798XDepartamento de Inmunología Pediátrica, Fundación Hospital Pediátrico La Misericordia, Bogotá, D.C., ColombiaDepartamento de Inmunología Pediátrica, Fundación Hospital Pediátrico La Misericordia, Bogotá, D.C., ColombiaDepartamento de Neumología Pediátrica, Fundación Hospital Pediátrico La Misericordia, Bogotá, D.C., Colombia; Departamento de Pediatría, Universidad Nacional de Colombia, Bogotá, D.C., ColombiaDepartamento de Cuidado Intensivo Pediátrico, Fundación Hospital Pediátrico La Misericordia, Bogotá, D.C., ColombiaDepartamento de Cuidado Intensivo Pediátrico, Fundación Hospital Pediátrico La Misericordia, Bogotá, D.C., ColombiaDepartamento de Cuidado Intensivo Pediátrico, Fundación Hospital Pediátrico La Misericordia, Bogotá, D.C., ColombiaDepartamento de Pediatría, Universidad Nacional de Colombia, Bogotá, D.C., ColombiaDepartamento de Pediatría, Universidad El Bosque, Bogotá, D.C., ColombiaDepartamento de Cuidado Intensivo Pediátrico, Fundación Hospital Pediátrico La Misericordia, Bogotá, D.C., ColombiaDepartamento de Infectología Pediátrica, Fundación Hospital Pediátrico La Misericordia, Bogotá, ColombiaDepartamento de Infectología Pediátrica, Fundación Hospital Pediátrico La Misericordia, Bogotá, ColombiaDepartamento de Infectología Pediátrica, Fundación Hospital Pediátrico La Misericordia, Bogotá, ColombiaDepartamento de Infectología Pediátrica, Clínica Infantil Colsubsidio, Bogotá, D.C., Colombia; Departamento de Infectología Pediátrica, Clínica Infantil Santa María del Lago, Bogotá, D.C., ColombiaDepartamento de Pediatría, Universidad Nacional de Colombia, Bogotá, D.C., Colombia; Departamento de Pediatría, Fundación Universitaria de Ciencias de la Salud, Bogotá, Colombia Departamento de Pediatría, Universidad Nacional de Colombia, Bogotá, D.C., Colombia; Departamento de Infectología Pediátrica, Fundación Hospital Pediátrico La Misericordia, Bogotá, ColombiaIntroduction. During the SARS-CoV-2 pandemic, many countries experienced decreased respiratory virus circulation, followed by an out-of-season outbreak. In a pediatric hospital in Colombia, we observed a surge in severe adenovirus infections, leading to concerns about the impact of eased public health restrictions and immune debt in children under five years old. Objective. To describe the clinical characteristics of patients with severe adenovirus infection in a pediatric hospital in Colombia. Materials and methods. We reviewed the data of 227 patients with severe adenovirus infection at the Fundación Hospital Pediátrico La Misericordia. Results. A total of 196 patients were included in this study. The median age was two years, and 62% were male. Adenoviruses were isolated from all patients’ samples. Ninetyseven percent were admitted to the pediatric intensive care unit, 94% required respiratory support, and the in-hospital lethality rate was 11%. Conclusion. In 2022, there was an outbreak of severe adenovirus infections, affecting mainly children under five years of age, with higher-than-usual mortality.https://revistabiomedica.org/index.php/biomedica/article/view/7047adenoviridae infectionspediatricsrespiratory insufficiencyshockanxiety, caregiver, family, intensive care unit, patient visits, policies.child |
| spellingShingle | Natalia Vélez-Tirado Lina Castaño-Jaramillo Sonia Restrepo-Gualteros Catalina Alcalá-Lozano Erika Ruge Carolina Puente Diana Li-Zeng Diego Chaparro-Arce María Camila Beltrán-Dimas Juan Francisco López Miguel Luengas-Monroy Diego Galvis-Trujillo Iván Gutiérrez-Tobar Pablo Vásquez-Hoyos Germán Camacho-Moreno Severe adenovirus infection outbreak in Colombia: Experience from a tertiary pediatric hospital in 2022 Biomédica: revista del Instituto Nacional de Salud adenoviridae infections pediatrics respiratory insufficiency shock anxiety, caregiver, family, intensive care unit, patient visits, policies. child |
| title | Severe adenovirus infection outbreak in Colombia: Experience from a tertiary pediatric hospital in 2022 |
| title_full | Severe adenovirus infection outbreak in Colombia: Experience from a tertiary pediatric hospital in 2022 |
| title_fullStr | Severe adenovirus infection outbreak in Colombia: Experience from a tertiary pediatric hospital in 2022 |
| title_full_unstemmed | Severe adenovirus infection outbreak in Colombia: Experience from a tertiary pediatric hospital in 2022 |
| title_short | Severe adenovirus infection outbreak in Colombia: Experience from a tertiary pediatric hospital in 2022 |
| title_sort | severe adenovirus infection outbreak in colombia experience from a tertiary pediatric hospital in 2022 |
| topic | adenoviridae infections pediatrics respiratory insufficiency shock anxiety, caregiver, family, intensive care unit, patient visits, policies. child |
| url | https://revistabiomedica.org/index.php/biomedica/article/view/7047 |
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