Focal Ischemic Injury to the Early Neonatal Rat Brain Models Cognitive and Motor Deficits with Associated Histopathological Outcomes Relevant to Human Neonatal Brain Injury

Focal Ischemic Injury to the Early Neonatal Rat Brain Models Cognitive and Motor Deficits with Associated Histopathological Outcomes Relevant to Human Neonatal Brain Injury

Neonatal arterial ischemic stroke is one of the more severe birth complications. The injury can result in extensive neurological damage and is robustly associated with later diagnoses of cerebral palsy (CP). An important part of efforts to develop new therapies include the on-going refinement and un...

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Bibliographic Details
Main Authors: Brett J. Kagan, Charlotte M. Ermine, Stefano Frausin, Clare L. Parish, Jess Nithianantharajah, Lachlan H. Thompson
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
endothelin-1
cerebral palsy
neonatal stroke
white matter injury
pairwise discrimination
touchscreen testing
Online Access:https://www.mdpi.com/1422-0067/22/9/4740

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