Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic accuracy.

Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic accuracy.

INTRODUCTION:An accurate and timely diagnosis for Alzheimer's disease (AD) is important, both for care and research. The current diagnostic criteria allow the use of CSF biomarkers to provide pathophysiological support for the diagnosis of AD. How these criteria should be operationalized by cli...

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Main Authors: Hanneke F M Rhodius-Meester, Ingrid S van Maurik, Juha Koikkalainen, Antti Tolonen, Kristian S Frederiksen, Steen G Hasselbalch, Hilkka Soininen, Sanna-Kaisa Herukka, Anne M Remes, Charlotte E Teunissen, Frederik Barkhof, Yolande A L Pijnenburg, Philip Scheltens, Jyrki Lötjönen, Wiesje M van der Flier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226784

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