Association of Periodontitis and Arterial Stiffness in Type 2 Diabetic Patients
Background: periodontitis is a major cause of chronic infection in diabetic patients. Diabetic patients have four-fold risk of having cardiovascular disease. Chronic inflammation caused by periodontitis, a non-traditional cardiovascular risk factor is widely known to play a major role in atherogenes...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2019-01-01
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| Series: | Acta Medica Indonesiana |
| Subjects: | |
| Online Access: | http://actamedindones.org/index.php/ijim/article/view/839 |
| _version_ | 1818118477653737472 |
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| author | Anandhara Indriani Khumaedi Dyah Purnamasari Ika P Wijaya Yuniarti Soeroso Siti Marhamah |
| author_facet | Anandhara Indriani Khumaedi Dyah Purnamasari Ika P Wijaya Yuniarti Soeroso Siti Marhamah |
| author_sort | Anandhara Indriani Khumaedi |
| collection | DOAJ |
| description | Background: periodontitis is a major cause of chronic infection in diabetic patients. Diabetic patients have four-fold risk of having cardiovascular disease. Chronic inflammation caused by periodontitis, a non-traditional cardiovascular risk factor is widely known to play a major role in atherogenesis. Among non-diabetics, an association has been found between periodontitis and arterial stiffness, but in diabetic patients the result is inconsistent. No study has investigated either the proportion of periodontitis or its correlation with arterial stiffness in type 2 diabetes population in Indonesia. Methods: this study was a cross-sectional study involving 97 patients with type 2 diabetics, who were recruited on Endocrinology Clinic from April to August 2017. Periodontitis was measured for pocket depth, clinical attachment loss and bleeding on probing by a periodontist. Carotid-femoral PWV (Pulse Wave Velocity) was measured using SphygmoCor Xcel with cuff-based tonometry technique. Results: periodontitis was found in 99% type 2 diabetic subjects and 78% of them had severe periodontitis. There was no significant correlation found between pocket depth, clinical attachment loss and cfPWV (r=0.024, p=0.407 and r=0.011, p=0.456); whereas there was a weak positive correlation between pocket depth and PWV (r=0.294, p=0.041) in well-controlled type 2 diabetics. Conclusion: most of type-2 diabetics had severe periodontitis; however, the correlation between periodontitis and arterial stiffness could not be concluded in this study. |
| first_indexed | 2024-12-11T04:54:56Z |
| format | Article |
| id | doaj.art-d2338b86ab9547c798be3a95696bf894 |
| institution | Directory Open Access Journal |
| issn | 0125-9326 2338-2732 |
| language | English |
| last_indexed | 2024-12-11T04:54:56Z |
| publishDate | 2019-01-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj.art-d2338b86ab9547c798be3a95696bf8942022-12-22T01:20:18ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322019-01-01504285Association of Periodontitis and Arterial Stiffness in Type 2 Diabetic PatientsAnandhara Indriani Khumaedi0Dyah Purnamasari1Ika P Wijaya2Yuniarti Soeroso3Siti Marhamah4Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.Department of Periodontia, Dentistry Unit, Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDepartment of Periodontia, Dentistry Unit, Cipto Mangunkusumo Hospital, Jakarta, IndonesiaBackground: periodontitis is a major cause of chronic infection in diabetic patients. Diabetic patients have four-fold risk of having cardiovascular disease. Chronic inflammation caused by periodontitis, a non-traditional cardiovascular risk factor is widely known to play a major role in atherogenesis. Among non-diabetics, an association has been found between periodontitis and arterial stiffness, but in diabetic patients the result is inconsistent. No study has investigated either the proportion of periodontitis or its correlation with arterial stiffness in type 2 diabetes population in Indonesia. Methods: this study was a cross-sectional study involving 97 patients with type 2 diabetics, who were recruited on Endocrinology Clinic from April to August 2017. Periodontitis was measured for pocket depth, clinical attachment loss and bleeding on probing by a periodontist. Carotid-femoral PWV (Pulse Wave Velocity) was measured using SphygmoCor Xcel with cuff-based tonometry technique. Results: periodontitis was found in 99% type 2 diabetic subjects and 78% of them had severe periodontitis. There was no significant correlation found between pocket depth, clinical attachment loss and cfPWV (r=0.024, p=0.407 and r=0.011, p=0.456); whereas there was a weak positive correlation between pocket depth and PWV (r=0.294, p=0.041) in well-controlled type 2 diabetics. Conclusion: most of type-2 diabetics had severe periodontitis; however, the correlation between periodontitis and arterial stiffness could not be concluded in this study.http://actamedindones.org/index.php/ijim/article/view/839periodontitispocket depthclinical attachment losspulse wave velocity (PWV) |
| spellingShingle | Anandhara Indriani Khumaedi Dyah Purnamasari Ika P Wijaya Yuniarti Soeroso Siti Marhamah Association of Periodontitis and Arterial Stiffness in Type 2 Diabetic Patients Acta Medica Indonesiana periodontitis pocket depth clinical attachment loss pulse wave velocity (PWV) |
| title | Association of Periodontitis and Arterial Stiffness in Type 2 Diabetic Patients |
| title_full | Association of Periodontitis and Arterial Stiffness in Type 2 Diabetic Patients |
| title_fullStr | Association of Periodontitis and Arterial Stiffness in Type 2 Diabetic Patients |
| title_full_unstemmed | Association of Periodontitis and Arterial Stiffness in Type 2 Diabetic Patients |
| title_short | Association of Periodontitis and Arterial Stiffness in Type 2 Diabetic Patients |
| title_sort | association of periodontitis and arterial stiffness in type 2 diabetic patients |
| topic | periodontitis pocket depth clinical attachment loss pulse wave velocity (PWV) |
| url | http://actamedindones.org/index.php/ijim/article/view/839 |
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