Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry

Medicinal plants play an important role in the treatment of a wide range of diseases, even if their chemical constituents are not always completely recognized. Observations on their use and efficacy significantly contribute to the disclosure of their therapeutic properties. Calamintha nepeta (L.) Sa...

Full description

Bibliographic Details
Main Authors: Mijat Božović, Rino Ragno
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/2/290
_version_ 1819090535566016512
author Mijat Božović
Rino Ragno
author_facet Mijat Božović
Rino Ragno
author_sort Mijat Božović
collection DOAJ
description Medicinal plants play an important role in the treatment of a wide range of diseases, even if their chemical constituents are not always completely recognized. Observations on their use and efficacy significantly contribute to the disclosure of their therapeutic properties. Calamintha nepeta (L.) Savi is an aromatic herb with a mint-oregano flavor, used in the Mediterranean areas as a traditional medicine. It has an extensive range of biological activities, including antimicrobial, antioxidant and anti-inflammatory, as well as anti-ulcer and insecticidal properties. This study aims to review the scientific findings and research reported to date on Calamintha nepeta (L.) Savi that prove many of the remarkable various biological actions, effects and some uses of this species as a source of bioactive natural compounds. On the other hand, pulegone, the major chemical constituent of Calamintha nepeta (L.) Savi essential oil, has been reported to exhibit numerous bioactivities in cells and animals. Thus, this integrated overview also surveys and interprets the present knowledge of chemistry and analysis of this oxygenated monoterpene, as well as its beneficial bioactivities. Areas for future research are suggested
first_indexed 2024-12-21T22:25:22Z
format Article
id doaj.art-d237f67c94564061a02ba47352d94994
institution Directory Open Access Journal
issn 1420-3049
language English
last_indexed 2024-12-21T22:25:22Z
publishDate 2017-02-01
publisher MDPI AG
record_format Article
series Molecules
spelling doaj.art-d237f67c94564061a02ba47352d949942022-12-21T18:48:14ZengMDPI AGMolecules1420-30492017-02-0122229010.3390/molecules22020290molecules22020290Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and ChemistryMijat Božović0Rino Ragno1Rome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, ItalyRome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, ItalyMedicinal plants play an important role in the treatment of a wide range of diseases, even if their chemical constituents are not always completely recognized. Observations on their use and efficacy significantly contribute to the disclosure of their therapeutic properties. Calamintha nepeta (L.) Savi is an aromatic herb with a mint-oregano flavor, used in the Mediterranean areas as a traditional medicine. It has an extensive range of biological activities, including antimicrobial, antioxidant and anti-inflammatory, as well as anti-ulcer and insecticidal properties. This study aims to review the scientific findings and research reported to date on Calamintha nepeta (L.) Savi that prove many of the remarkable various biological actions, effects and some uses of this species as a source of bioactive natural compounds. On the other hand, pulegone, the major chemical constituent of Calamintha nepeta (L.) Savi essential oil, has been reported to exhibit numerous bioactivities in cells and animals. Thus, this integrated overview also surveys and interprets the present knowledge of chemistry and analysis of this oxygenated monoterpene, as well as its beneficial bioactivities. Areas for future research are suggestedhttp://www.mdpi.com/1420-3049/22/2/290Calamintha nepeta (L.) Saviessential oilextractpulegonebiological activity
spellingShingle Mijat Božović
Rino Ragno
Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry
Molecules
Calamintha nepeta (L.) Savi
essential oil
extract
pulegone
biological activity
title Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry
title_full Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry
title_fullStr Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry
title_full_unstemmed Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry
title_short Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry
title_sort calamintha nepeta l savi and its main essential oil constituent pulegone biological activities and chemistry
topic Calamintha nepeta (L.) Savi
essential oil
extract
pulegone
biological activity
url http://www.mdpi.com/1420-3049/22/2/290
work_keys_str_mv AT mijatbozovic calaminthanepetalsavianditsmainessentialoilconstituentpulegonebiologicalactivitiesandchemistry
AT rinoragno calaminthanepetalsavianditsmainessentialoilconstituentpulegonebiologicalactivitiesandchemistry