The silencing of Pokemon attenuates the proliferation of hepatocellular carcinoma cells in vitro and in vivo by inhibiting the PI3K/Akt pathway.
Pokemon (POK erythroid myeloid ontogenic factor), which belongs to the POK protein family, is also called LRF, OCZF and FBI-1. As a transcriptional repressor, Pokemon assumes a critical function in cellular differentiation and oncogenesis. Our study identified an oncogenic role for Pokemon in human...
Main Authors: | Chan-Chan Lin, Jing-Ping Zhou, Yun-Peng Liu, Jing-Jing Liu, Xiao-Ning Yang, Amarsanaa Jazag, Zhi-Ping Zhang, Bayasi Guleng, Jian-Lin Ren |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3530584?pdf=render |
Similar Items
-
Peach gum polysaccharides promotes epithelial proliferation to attenuate ulcerative colitis by PI3K/AKT pathway
by: Xiaobo Lin, et al.
Published: (2023-08-01) -
ncRNAs-mediated high expression of TICRR promotes tumor cell proliferation and migration and is correlated with poor prognosis and tumor immune infiltration of hepatocellular carcinoma
by: Ke-Jie He, et al.
Published: (2022-12-01) -
Silencing of Peroxiredoxin 1 Inhibits the Proliferation of Esophageal Cancer Cells and Promotes Apoptosis by Inhibiting the Activity of the PI3K/AKT Pathway
by: Song Y, et al.
Published: (2019-12-01) -
Effects of LAIR‐1 on hepatocellular carcinoma cell proliferation and invasion via PI3K‐AKT‐mTOR pathway regulation
by: Ti Zhou, et al.
Published: (2023-08-01) -
Pentamidine inhibits proliferation, migration and invasion in endometrial cancer via the PI3K/AKT signaling pathway
by: Lin Lin, et al.
Published: (2022-11-01)