Anopheles bionomics, insecticide resistance mechanisms, and malaria transmission in the Korhogo area, northern Côte d’Ivoire: a pre-intervention study
A better understanding of malaria transmission at a local scale is essential for developing and implementing effective control strategies. In the framework of a randomized controlled trial (RCT), we aimed to provide an updated description of malaria transmission in the Korhogo area, northern Côte d’...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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EDP Sciences
2019-01-01
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| Series: | Parasite |
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| Online Access: | https://www.parasite-journal.org/articles/parasite/full_html/2019/01/parasite190038/parasite190038.html |
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| author | Zogo Barnabas Soma Dieudonné Diloma Tchiekoi Bertin N’Cho Somé Anthony Ahoua Alou Ludovic P. Koffi Alphonsine A. Fournet Florence Dahounto Amal Coulibaly Baba Kandé Souleymane Dabiré Roch Kounbobr Baba-Moussa Lamine Moiroux Nicolas Pennetier Cédric |
| author_facet | Zogo Barnabas Soma Dieudonné Diloma Tchiekoi Bertin N’Cho Somé Anthony Ahoua Alou Ludovic P. Koffi Alphonsine A. Fournet Florence Dahounto Amal Coulibaly Baba Kandé Souleymane Dabiré Roch Kounbobr Baba-Moussa Lamine Moiroux Nicolas Pennetier Cédric |
| author_sort | Zogo Barnabas |
| collection | DOAJ |
| description | A better understanding of malaria transmission at a local scale is essential for developing and implementing effective control strategies. In the framework of a randomized controlled trial (RCT), we aimed to provide an updated description of malaria transmission in the Korhogo area, northern Côte d’Ivoire, and to obtain baseline data for the trial. We performed human landing collections (HLCs) in 26 villages in the Korhogo area during the rainy season (September–October 2016, April–May 2017) and the dry season (November–December 2016, February–March 2017). We used PCR techniques to ascertain the species of the Anopheles gambiae complex, Plasmodium falciparum sporozoite infection, and insecticide resistance mechanisms in a subset of Anopheles vectors. Anopheles gambiae s.l. was the predominant malaria vector in the Korhogo area. Overall, more vectors were collected outdoors than indoors (p < 0.001). Of the 774 An. gambiae s.l. tested in the laboratory, 89.65% were An. gambiae s.s. and 10.35% were An. coluzzii. The frequencies of the kdr allele were very high in An. gambiae s.s. but the ace-1 allele was found at moderate frequencies. An unprotected individual living in the Korhogo area received an average of 9.04, 0.63, 0.06 and 0.12 infected bites per night in September–October, November–December, February–March, and April–May, respectively. These results demonstrate that the intensity of malaria transmission is extremely high in the Korhogo area, especially during the rainy season. Malaria control in highly endemic areas such as Korhogo needs to be strengthened with complementary tools in order to reduce the burden of the disease. |
| first_indexed | 2024-03-11T14:07:37Z |
| format | Article |
| id | doaj.art-d23e8fc030cd450a87a9f01dcebf1b59 |
| institution | Directory Open Access Journal |
| issn | 1776-1042 |
| language | English |
| last_indexed | 2024-03-11T14:07:37Z |
| publishDate | 2019-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | Parasite |
| spelling | doaj.art-d23e8fc030cd450a87a9f01dcebf1b592023-11-02T01:40:21ZengEDP SciencesParasite1776-10422019-01-01264010.1051/parasite/2019040parasite190038Anopheles bionomics, insecticide resistance mechanisms, and malaria transmission in the Korhogo area, northern Côte d’Ivoire: a pre-intervention studyZogo BarnabasSoma Dieudonné DilomaTchiekoi Bertin N’ChoSomé AnthonyAhoua Alou Ludovic P.Koffi Alphonsine A.Fournet FlorenceDahounto AmalCoulibaly BabaKandé SouleymaneDabiré Roch KounbobrBaba-Moussa LamineMoiroux NicolasPennetier CédricA better understanding of malaria transmission at a local scale is essential for developing and implementing effective control strategies. In the framework of a randomized controlled trial (RCT), we aimed to provide an updated description of malaria transmission in the Korhogo area, northern Côte d’Ivoire, and to obtain baseline data for the trial. We performed human landing collections (HLCs) in 26 villages in the Korhogo area during the rainy season (September–October 2016, April–May 2017) and the dry season (November–December 2016, February–March 2017). We used PCR techniques to ascertain the species of the Anopheles gambiae complex, Plasmodium falciparum sporozoite infection, and insecticide resistance mechanisms in a subset of Anopheles vectors. Anopheles gambiae s.l. was the predominant malaria vector in the Korhogo area. Overall, more vectors were collected outdoors than indoors (p < 0.001). Of the 774 An. gambiae s.l. tested in the laboratory, 89.65% were An. gambiae s.s. and 10.35% were An. coluzzii. The frequencies of the kdr allele were very high in An. gambiae s.s. but the ace-1 allele was found at moderate frequencies. An unprotected individual living in the Korhogo area received an average of 9.04, 0.63, 0.06 and 0.12 infected bites per night in September–October, November–December, February–March, and April–May, respectively. These results demonstrate that the intensity of malaria transmission is extremely high in the Korhogo area, especially during the rainy season. Malaria control in highly endemic areas such as Korhogo needs to be strengthened with complementary tools in order to reduce the burden of the disease.https://www.parasite-journal.org/articles/parasite/full_html/2019/01/parasite190038/parasite190038.htmlMalariaVectorsResistanceIntensity of transmission |
| spellingShingle | Zogo Barnabas Soma Dieudonné Diloma Tchiekoi Bertin N’Cho Somé Anthony Ahoua Alou Ludovic P. Koffi Alphonsine A. Fournet Florence Dahounto Amal Coulibaly Baba Kandé Souleymane Dabiré Roch Kounbobr Baba-Moussa Lamine Moiroux Nicolas Pennetier Cédric Anopheles bionomics, insecticide resistance mechanisms, and malaria transmission in the Korhogo area, northern Côte d’Ivoire: a pre-intervention study Parasite Malaria Vectors Resistance Intensity of transmission |
| title | Anopheles bionomics, insecticide resistance mechanisms, and malaria transmission in the Korhogo area, northern Côte d’Ivoire: a pre-intervention study |
| title_full | Anopheles bionomics, insecticide resistance mechanisms, and malaria transmission in the Korhogo area, northern Côte d’Ivoire: a pre-intervention study |
| title_fullStr | Anopheles bionomics, insecticide resistance mechanisms, and malaria transmission in the Korhogo area, northern Côte d’Ivoire: a pre-intervention study |
| title_full_unstemmed | Anopheles bionomics, insecticide resistance mechanisms, and malaria transmission in the Korhogo area, northern Côte d’Ivoire: a pre-intervention study |
| title_short | Anopheles bionomics, insecticide resistance mechanisms, and malaria transmission in the Korhogo area, northern Côte d’Ivoire: a pre-intervention study |
| title_sort | anopheles bionomics insecticide resistance mechanisms and malaria transmission in the korhogo area northern cote d ivoire a pre intervention study |
| topic | Malaria Vectors Resistance Intensity of transmission |
| url | https://www.parasite-journal.org/articles/parasite/full_html/2019/01/parasite190038/parasite190038.html |
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