α-Linolenic acid induces apoptosis, inhibits the invasion and metastasis, and arrests cell cycle in human breast cancer cells by inhibiting fatty acid synthase

α-Linolenic acid induces apoptosis, inhibits the invasion and metastasis, and arrests cell cycle in human breast cancer cells by inhibiting fatty acid synthase

Fatty acid synthase (FASN) is an enzyme that synthesizes endogenous fatty acids. FASN overexpressed in various cancers, which indicates the involvement of FASN in cancer progression. α-Linolenic acid (ALA) is an omega-3 fatty acid with many biological activities, including anti-cancer effects. The a...

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Bibliographic Details
Main Authors: Wenyuan Huang, Xing Guo, Chunyan Wang, Amantay Alzhan, Zhengan Liu, Xiaofeng Ma, Qingyan Shu
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Journal of Functional Foods
Subjects:
Fatty acid synthase
α-Linolenic acid
Inhibitor
Breast cancer cells
Cell apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622001116

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