Palladium-catalyzed cyclobutenation of aryl chlorides with norbornenes
A palladium-catalyzed cyclobutenation of readily available aryl chlorides and norbornene derivatives is reported here. Under the optimum reaction conditions, various valuable benzocyclobutene derivatives were prepared efficiently via Heck-Catellani reaction. The key is the employment of bulky t-Bu3P...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co. Ltd.
2022-02-01
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| Series: | Green Synthesis and Catalysis |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666554921000934 |
| _version_ | 1819119961729138688 |
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| author | Zhenkun Chen Mingruo Ding Haobin Jiang Fengzhi Zhang |
| author_facet | Zhenkun Chen Mingruo Ding Haobin Jiang Fengzhi Zhang |
| author_sort | Zhenkun Chen |
| collection | DOAJ |
| description | A palladium-catalyzed cyclobutenation of readily available aryl chlorides and norbornene derivatives is reported here. Under the optimum reaction conditions, various valuable benzocyclobutene derivatives were prepared efficiently via Heck-Catellani reaction. The key is the employment of bulky t-Bu3PHBF4 phosphine ligand which promoted C–C reductive elimination from the palladacycle. |
| first_indexed | 2024-12-22T06:13:05Z |
| format | Article |
| id | doaj.art-d240d0961e27400195b18ab5eccee27d |
| institution | Directory Open Access Journal |
| issn | 2666-5549 |
| language | English |
| last_indexed | 2024-12-22T06:13:05Z |
| publishDate | 2022-02-01 |
| publisher | KeAi Communications Co. Ltd. |
| record_format | Article |
| series | Green Synthesis and Catalysis |
| spelling | doaj.art-d240d0961e27400195b18ab5eccee27d2022-12-21T18:36:10ZengKeAi Communications Co. Ltd.Green Synthesis and Catalysis2666-55492022-02-01317983Palladium-catalyzed cyclobutenation of aryl chlorides with norbornenesZhenkun Chen0Mingruo Ding1Haobin Jiang2Fengzhi Zhang3College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, ChinaCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, ChinaCollege of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, ChinaCorresponding author.; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, ChinaA palladium-catalyzed cyclobutenation of readily available aryl chlorides and norbornene derivatives is reported here. Under the optimum reaction conditions, various valuable benzocyclobutene derivatives were prepared efficiently via Heck-Catellani reaction. The key is the employment of bulky t-Bu3PHBF4 phosphine ligand which promoted C–C reductive elimination from the palladacycle.http://www.sciencedirect.com/science/article/pii/S2666554921000934Palladium catalysisCyclobutenationC–H activationHeck-Catellani reaction |
| spellingShingle | Zhenkun Chen Mingruo Ding Haobin Jiang Fengzhi Zhang Palladium-catalyzed cyclobutenation of aryl chlorides with norbornenes Green Synthesis and Catalysis Palladium catalysis Cyclobutenation C–H activation Heck-Catellani reaction |
| title | Palladium-catalyzed cyclobutenation of aryl chlorides with norbornenes |
| title_full | Palladium-catalyzed cyclobutenation of aryl chlorides with norbornenes |
| title_fullStr | Palladium-catalyzed cyclobutenation of aryl chlorides with norbornenes |
| title_full_unstemmed | Palladium-catalyzed cyclobutenation of aryl chlorides with norbornenes |
| title_short | Palladium-catalyzed cyclobutenation of aryl chlorides with norbornenes |
| title_sort | palladium catalyzed cyclobutenation of aryl chlorides with norbornenes |
| topic | Palladium catalysis Cyclobutenation C–H activation Heck-Catellani reaction |
| url | http://www.sciencedirect.com/science/article/pii/S2666554921000934 |
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