Advances in pathogenesis and clinical features of HIV-associated neuroretinal disorder
Ocular diseases in human immunodeficiency virus(HIV)infected patients have attracted increasing attention due to their impact on quality of life. As HIV treatment continues to improve, opportunistic eye infections are decreasing, while HIV-associated retinopathy is becoming a growing concern. HIV-as...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2022-04-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://ies.ijo.cn/cn_publish/2022/4/202204014.pdf |
| _version_ | 1818313092050714624 |
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| author | Yue Zou Ying-Xing Zhu Li-Bo Xiao Yun-Qin Li |
| author_facet | Yue Zou Ying-Xing Zhu Li-Bo Xiao Yun-Qin Li |
| author_sort | Yue Zou |
| collection | DOAJ |
| description | Ocular diseases in human immunodeficiency virus(HIV)infected patients have attracted increasing attention due to their impact on quality of life. As HIV treatment continues to improve, opportunistic eye infections are decreasing, while HIV-associated retinopathy is becoming a growing concern. HIV-associated retinopathy, including a series of structural changes in the retina and optic nerves(thinning of the nerve fiber layer, changing in blood vessels), has been found to cause decreased visual sensitivity, visual field defect, color vision disorder. However, the pathogenesis of HIV-associated neuroretinal disorder has not been fully clarified, and the existing findings may be related to direct destruction of retinal optic nerve tissue by HIV virus, chronic inflammation, and destruction of the blood-retina barrier. Understanding the pathological characteristics and possible mechanisms of HIV-associated neuroretinal disorder is expected to provide new ideas and approaches for the treatment of the disease and improve the quality of life of HIV-infected patients. |
| first_indexed | 2024-12-13T08:28:15Z |
| format | Article |
| id | doaj.art-d241b80daed745478a306aedc01ac165 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-12-13T08:28:15Z |
| publishDate | 2022-04-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-d241b80daed745478a306aedc01ac1652022-12-21T23:53:51ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232022-04-0122459760010.3980/j.issn.1672-5123.2022.4.14202204014Advances in pathogenesis and clinical features of HIV-associated neuroretinal disorderYue Zou0Ying-Xing Zhu1Li-Bo Xiao2Yun-Qin Li3Department of Ophthalmology, Affiliated Hospital of Yunnan University, Kunming 650021, Yunnan Province, China; Yunnan Eye Disease Clinical Medical Center, Kunming 650021, Yunnan Province, China; Yunnan Eye Disease Clinical Medical Research Center, Kunming 650021, Yunnan Province, ChinaDepartment of Ophthalmology, Affiliated Hospital of Yunnan University, Kunming 650021, Yunnan Province, ChinaDepartment of Ophthalmology, Affiliated Hospital of Yunnan University, Kunming 650021, Yunnan Province, China; Yunnan Eye Disease Clinical Medical Center, Kunming 650021, Yunnan Province, China; Yunnan Eye Disease Clinical Medical Research Center, Kunming 650021, Yunnan Province, ChinaDepartment of Ophthalmology, Affiliated Hospital of Yunnan University, Kunming 650021, Yunnan Province, China; Yunnan Eye Disease Clinical Medical Center, Kunming 650021, Yunnan Province, China; Yunnan Eye Disease Clinical Medical Research Center, Kunming 650021, Yunnan Province, ChinaOcular diseases in human immunodeficiency virus(HIV)infected patients have attracted increasing attention due to their impact on quality of life. As HIV treatment continues to improve, opportunistic eye infections are decreasing, while HIV-associated retinopathy is becoming a growing concern. HIV-associated retinopathy, including a series of structural changes in the retina and optic nerves(thinning of the nerve fiber layer, changing in blood vessels), has been found to cause decreased visual sensitivity, visual field defect, color vision disorder. However, the pathogenesis of HIV-associated neuroretinal disorder has not been fully clarified, and the existing findings may be related to direct destruction of retinal optic nerve tissue by HIV virus, chronic inflammation, and destruction of the blood-retina barrier. Understanding the pathological characteristics and possible mechanisms of HIV-associated neuroretinal disorder is expected to provide new ideas and approaches for the treatment of the disease and improve the quality of life of HIV-infected patients.http://ies.ijo.cn/cn_publish/2022/4/202204014.pdfhuman immunodeficiency virus(hiv)neuroretinal disorderclinical features |
| spellingShingle | Yue Zou Ying-Xing Zhu Li-Bo Xiao Yun-Qin Li Advances in pathogenesis and clinical features of HIV-associated neuroretinal disorder Guoji Yanke Zazhi human immunodeficiency virus(hiv) neuroretinal disorder clinical features |
| title | Advances in pathogenesis and clinical features of HIV-associated neuroretinal disorder |
| title_full | Advances in pathogenesis and clinical features of HIV-associated neuroretinal disorder |
| title_fullStr | Advances in pathogenesis and clinical features of HIV-associated neuroretinal disorder |
| title_full_unstemmed | Advances in pathogenesis and clinical features of HIV-associated neuroretinal disorder |
| title_short | Advances in pathogenesis and clinical features of HIV-associated neuroretinal disorder |
| title_sort | advances in pathogenesis and clinical features of hiv associated neuroretinal disorder |
| topic | human immunodeficiency virus(hiv) neuroretinal disorder clinical features |
| url | http://ies.ijo.cn/cn_publish/2022/4/202204014.pdf |
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