FNR-Dependent RmpA and RmpA2 Regulation of Capsule Polysaccharide Biosynthesis in Klebsiella pneumoniae

FNR-Dependent RmpA and RmpA2 Regulation of Capsule Polysaccharide Biosynthesis in Klebsiella pneumoniae

Fumarate nitrate reduction regulator (FNR) is a direct oxygen-responsive transcriptional regulator containing an iron-sulfur (Fe–S) cluster. During anaerobic growth, the [4Fe–4S] cluster in FNR (holo-FNR) binds specifically to DNA, whereas exposure to oxygen results in the loss of its DNA-binding ac...

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Bibliographic Details
Main Authors: Tien-Huang Lin, Chien-Chen Wu, Jong-Tar Kuo, Hsu-Feng Chu, Ding-Yu Lee, Ching-Ting Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Microbiology
Subjects:
Klebsiella pneumoniae
oxygen
FNR
capsule polysaccharide
RmpA
RmpA2
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02436/full

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