Extracellular Vesicles of Human Periodontal Ligament Stem Cells Contain MicroRNAs Associated to Proto-Oncogenes: Implications in Cytokinesis

Extracellular Vesicles of Human Periodontal Ligament Stem Cells Contain MicroRNAs Associated to Proto-Oncogenes: Implications in Cytokinesis

The human Periodontal Ligament Stem Cells (hPDLSCs) exhibit self-renewal capacity and clonogenicity potential. The Extracellular Vesicles (EVs) secreted by hPDLSCs are particles containing lipids, proteins, mRNAs, and non-coding RNAs, among which microRNAs, that are important in intercellular commun...

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Bibliographic Details
Main Authors: Luigi Chiricosta, Serena Silvestro, Agnese Gugliandolo, Guya Diletta Marconi, Jacopo Pizzicannella, Placido Bramanti, Oriana Trubiani, Emanuela Mazzon
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Genetics
Subjects:
human periodontal ligament stem cells
extracellular vesicles
next generation sequencing
non-coding RNAs
microRNAs
cytokinesis
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00582/full

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