Vaccine hesitancy with a history of Guillain Barre Syndrome: Weighing the risks and benefits of SARS-CoV-2 vaccination

Since the beginning of the COVID-19 pandemic, great hesitancies regarding the COVID-19 immunization have existed. The most striking adverse events reported include thrombosis with thrombocytopenia syndrome (TTS), myocarditis, and Guillain Barre Syndrome (GBS). Post-vaccination GBS is known since the...

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Main Authors: Aleksandra Murawska Baptista, Akankcha Alok, Claudia Libertin
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:IDCases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250922000956
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author Aleksandra Murawska Baptista
Akankcha Alok
Claudia Libertin
author_facet Aleksandra Murawska Baptista
Akankcha Alok
Claudia Libertin
author_sort Aleksandra Murawska Baptista
collection DOAJ
description Since the beginning of the COVID-19 pandemic, great hesitancies regarding the COVID-19 immunization have existed. The most striking adverse events reported include thrombosis with thrombocytopenia syndrome (TTS), myocarditis, and Guillain Barre Syndrome (GBS). Post-vaccination GBS is known since the time of Influenza vaccination, but several cases of GBS have also been reported in the current COVID-19 vaccination era. As a result, our patient with a history of GBS post-Influenza vaccination, went unvaccinated for SARS-CoV-2, due to fear of GBS re-activation. Consequently, he contracted COVID-19 pneumonitis complicated with deep venous thrombosis, requiring a prolonged hospitalization. Weighing the risks and benefits of vaccination to COVID-19 is difficult, especially for people with a previous history of GBS related to Influenza vaccination. We reviewed and analyzed the reported cases of GBS temporary related to COVID-19 vaccination to determine the safety of their administration in those with a history of GBS.
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spelling doaj.art-d250cac9aa7946c8b39784630fa555b92022-12-22T00:24:12ZengElsevierIDCases2214-25092022-01-0128e01467Vaccine hesitancy with a history of Guillain Barre Syndrome: Weighing the risks and benefits of SARS-CoV-2 vaccinationAleksandra Murawska Baptista0Akankcha Alok1Claudia Libertin2Mayo Clinic Alix School of Medicine, Department of Internal Medicine, 4500 San Pablo Rd S, Jacksonville, FL 32224, USA; Corresponding author.Mayo Clinic, 4500 San Pablo Rd S, Jacksonville, FL 32224, USAMayo Clinic Alix School of Medicine, Division of Infectious Diseases, 4500 San Pablo Rd S, Jacksonville, FL 32224, USASince the beginning of the COVID-19 pandemic, great hesitancies regarding the COVID-19 immunization have existed. The most striking adverse events reported include thrombosis with thrombocytopenia syndrome (TTS), myocarditis, and Guillain Barre Syndrome (GBS). Post-vaccination GBS is known since the time of Influenza vaccination, but several cases of GBS have also been reported in the current COVID-19 vaccination era. As a result, our patient with a history of GBS post-Influenza vaccination, went unvaccinated for SARS-CoV-2, due to fear of GBS re-activation. Consequently, he contracted COVID-19 pneumonitis complicated with deep venous thrombosis, requiring a prolonged hospitalization. Weighing the risks and benefits of vaccination to COVID-19 is difficult, especially for people with a previous history of GBS related to Influenza vaccination. We reviewed and analyzed the reported cases of GBS temporary related to COVID-19 vaccination to determine the safety of their administration in those with a history of GBS.http://www.sciencedirect.com/science/article/pii/S2214250922000956COVID-19 infectionCOVID-19 vaccinesGuillain Barre SyndromeImmunization
spellingShingle Aleksandra Murawska Baptista
Akankcha Alok
Claudia Libertin
Vaccine hesitancy with a history of Guillain Barre Syndrome: Weighing the risks and benefits of SARS-CoV-2 vaccination
IDCases
COVID-19 infection
COVID-19 vaccines
Guillain Barre Syndrome
Immunization
title Vaccine hesitancy with a history of Guillain Barre Syndrome: Weighing the risks and benefits of SARS-CoV-2 vaccination
title_full Vaccine hesitancy with a history of Guillain Barre Syndrome: Weighing the risks and benefits of SARS-CoV-2 vaccination
title_fullStr Vaccine hesitancy with a history of Guillain Barre Syndrome: Weighing the risks and benefits of SARS-CoV-2 vaccination
title_full_unstemmed Vaccine hesitancy with a history of Guillain Barre Syndrome: Weighing the risks and benefits of SARS-CoV-2 vaccination
title_short Vaccine hesitancy with a history of Guillain Barre Syndrome: Weighing the risks and benefits of SARS-CoV-2 vaccination
title_sort vaccine hesitancy with a history of guillain barre syndrome weighing the risks and benefits of sars cov 2 vaccination
topic COVID-19 infection
COVID-19 vaccines
Guillain Barre Syndrome
Immunization
url http://www.sciencedirect.com/science/article/pii/S2214250922000956
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