Pattern of acute glomerulonephritis in adult population in Dubai: A single-center experience
Epidemiological data of renal diseases have great geographic variability throughout the world. Due to the lack of a national renal data registry system, there is no information on the prevalence rate, clinical and pathological features of various glomerulonephritis (GN) in the United Arab Emirates (...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2017;volume=28;issue=3;spage=571;epage=578;aulast=Alhadari |
| _version_ | 1811193261169049600 |
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| author | Amna K Alhadari Fakhriya J Alalawi Ayman Aly Seddik Kaneez Zahra Dileep Kumar Hussain Yousif Hind Alnour Michael Jansen Mohammad J Railey |
| author_facet | Amna K Alhadari Fakhriya J Alalawi Ayman Aly Seddik Kaneez Zahra Dileep Kumar Hussain Yousif Hind Alnour Michael Jansen Mohammad J Railey |
| author_sort | Amna K Alhadari |
| collection | DOAJ |
| description | Epidemiological data of renal diseases have great geographic variability throughout the world. Due to the lack of a national renal data registry system, there is no information on the prevalence rate, clinical and pathological features of various glomerulonephritis (GN) in the United Arab Emirates (UAE). In a retrospective cross-sectional study, we analyzed 158 renal biopsies done in Dubai Hospital, UAE, between the years of 2005 and September 2014, with an aim to determine the prevalence rate and frequency of different pathological patterns of GN in adult patients who presented with proteinuria ± hematuria. In our study, primary GN still remains more common than secondary GN (66.4% vs. 33.5%). Among the primary GN in our analysis, minimal change disease was the most common primary GN affecting 20% of the study population (13.2% of the total GN causes) followed with membranous GN (18.2%), then membrano- proliferative GN (15.3%) and focal segmental glomerulosclerosis (13.46%), while among the secondary causes lupus nephritis (LN) is the most prevalent GN in UAE, predominantly in the Emirati national population whom constituted 48% of total biopsies. Indeed, LN had the highest incidence among all types of GN even the primary ones, constituting 23.4% of total GN in Dubai (74% of the total secondary causes). Furthermore, systemic lupus erythematosus was the most common GN in women while the minimal change was widely affecting male patients. Among elderly, the most common pathology was diabetic glomerulosclerosis followed by amyloidosis. |
| first_indexed | 2024-04-12T00:05:27Z |
| format | Article |
| id | doaj.art-d252391850914a4d9d529f48cbe414ec |
| institution | Directory Open Access Journal |
| issn | 1319-2442 |
| language | English |
| last_indexed | 2024-04-12T00:05:27Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-d252391850914a4d9d529f48cbe414ec2022-12-22T03:56:08ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422017-01-0128357157810.4103/1319-2442.206443Pattern of acute glomerulonephritis in adult population in Dubai: A single-center experienceAmna K AlhadariFakhriya J AlalawiAyman Aly SeddikKaneez ZahraDileep KumarHussain YousifHind AlnourMichael JansenMohammad J RaileyEpidemiological data of renal diseases have great geographic variability throughout the world. Due to the lack of a national renal data registry system, there is no information on the prevalence rate, clinical and pathological features of various glomerulonephritis (GN) in the United Arab Emirates (UAE). In a retrospective cross-sectional study, we analyzed 158 renal biopsies done in Dubai Hospital, UAE, between the years of 2005 and September 2014, with an aim to determine the prevalence rate and frequency of different pathological patterns of GN in adult patients who presented with proteinuria ± hematuria. In our study, primary GN still remains more common than secondary GN (66.4% vs. 33.5%). Among the primary GN in our analysis, minimal change disease was the most common primary GN affecting 20% of the study population (13.2% of the total GN causes) followed with membranous GN (18.2%), then membrano- proliferative GN (15.3%) and focal segmental glomerulosclerosis (13.46%), while among the secondary causes lupus nephritis (LN) is the most prevalent GN in UAE, predominantly in the Emirati national population whom constituted 48% of total biopsies. Indeed, LN had the highest incidence among all types of GN even the primary ones, constituting 23.4% of total GN in Dubai (74% of the total secondary causes). Furthermore, systemic lupus erythematosus was the most common GN in women while the minimal change was widely affecting male patients. Among elderly, the most common pathology was diabetic glomerulosclerosis followed by amyloidosis.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2017;volume=28;issue=3;spage=571;epage=578;aulast=Alhadari |
| spellingShingle | Amna K Alhadari Fakhriya J Alalawi Ayman Aly Seddik Kaneez Zahra Dileep Kumar Hussain Yousif Hind Alnour Michael Jansen Mohammad J Railey Pattern of acute glomerulonephritis in adult population in Dubai: A single-center experience Saudi Journal of Kidney Diseases and Transplantation |
| title | Pattern of acute glomerulonephritis in adult population in Dubai: A single-center experience |
| title_full | Pattern of acute glomerulonephritis in adult population in Dubai: A single-center experience |
| title_fullStr | Pattern of acute glomerulonephritis in adult population in Dubai: A single-center experience |
| title_full_unstemmed | Pattern of acute glomerulonephritis in adult population in Dubai: A single-center experience |
| title_short | Pattern of acute glomerulonephritis in adult population in Dubai: A single-center experience |
| title_sort | pattern of acute glomerulonephritis in adult population in dubai a single center experience |
| url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2017;volume=28;issue=3;spage=571;epage=578;aulast=Alhadari |
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