Comparison of laboratory parameters in children admitted with febrile seizures and fever without localized sign in Urmia Motahari hospital, Iran, 2015 until 2020

Background. Febrile seizures are the most common childhood seizure disorder, occurring in 3 to 15% of children. The present study investigated the laboratory parameters in children admitted with febrile seizure and those with fever without localized sign (FWLS) in Shahid Motahari Hospital in Urmia....

Full description

Bibliographic Details
Main Authors: Ezatollah Abbasi, Ahad Ghazavi, Asma Firoozi
Format: Article
Language:fas
Published: Tabriz University of Medical Sciences 2022-04-01
Series:مجله پزشکی دانشگاه علوم پزشکی تبریز
Subjects:
Online Access:https://mj.tbzmed.ac.ir/PDF/mj-44-47.pdf
_version_ 1798039949719633920
author Ezatollah Abbasi
Ahad Ghazavi
Asma Firoozi
author_facet Ezatollah Abbasi
Ahad Ghazavi
Asma Firoozi
author_sort Ezatollah Abbasi
collection DOAJ
description Background. Febrile seizures are the most common childhood seizure disorder, occurring in 3 to 15% of children. The present study investigated the laboratory parameters in children admitted with febrile seizure and those with fever without localized sign (FWLS) in Shahid Motahari Hospital in Urmia. Methods. Demographic and clinical data of all patients admitted to the pediatric ward of Shahid Motahari Hospital in Urmia from 2015 to 2020 with febrile seizure and fever without localized sign (FWLS) were collected. Levels of BUN, creatinine, blood sugar, sodium, potassium , calcium , C reactive protein (CRP), neutrophil count, lymphocyte count, white blood cell count, hematocrit, platelets, ESR (Erythrocyte sedimentation rate ) and UA (urine analysis) and UC(urine cuiture), test results were also extracted from patients' file. Finally, the data extracted were compared between patients with febrile seizure and fever without localized sign (FWLS) cohort. Results. In this study, a total of 425 people were included, of which 185 were in the Febrile seizures group (case) and 240 were in the fever without localized sign (FWLS) (control) cohort, with 220 (51.8%) being male and 205 (48.2%) female. The mean age for all subjects was 20.62 ±4.84 months. There was a significant difference between the two groups in terms of mean levels of BUN (P=0.041), creatinine (P=0.006), ESR (P<0.001) and CRP (P<0.001); The mean levels of BUN and creatinine in patients with febrile seizures were significantly higher than patients with fever without localized sign (FWLS) and the mean ESR and CRP in patients with fever without localized sign (FWLS) were significantly higher than patients with febrile seizures. Conclusion. There is a significant difference in BUN, creatinine, ESR and CRP levels between patients with febrile seizure and fever without localized sign (FWLS), which can be used to predict the course of fever in children. Practical Implications. None of the laboratory parameters predict the onset of fever and seizures following a simple fever.
first_indexed 2024-04-11T22:00:45Z
format Article
id doaj.art-d254c587a9964017b6cd809eb0779196
institution Directory Open Access Journal
issn 2783-2031
2783-204X
language fas
last_indexed 2024-04-11T22:00:45Z
publishDate 2022-04-01
publisher Tabriz University of Medical Sciences
record_format Article
series مجله پزشکی دانشگاه علوم پزشکی تبریز
spelling doaj.art-d254c587a9964017b6cd809eb07791962022-12-22T04:00:56ZfasTabriz University of Medical Sciencesمجله پزشکی دانشگاه علوم پزشکی تبریز2783-20312783-204X2022-04-01441475410.34172/mj.2022.013mj-27656Comparison of laboratory parameters in children admitted with febrile seizures and fever without localized sign in Urmia Motahari hospital, Iran, 2015 until 2020Ezatollah Abbasi0Ahad Ghazavi1Asma Firoozi2Faculty of Medicine, Urmia University of Medical Sciences, Urmia, IranNeurophysiology Research Center, Urmia University of Medical Sciences, Urmia, IranMedical Student, Urmia University of Medical Sciences, Urmia, IranBackground. Febrile seizures are the most common childhood seizure disorder, occurring in 3 to 15% of children. The present study investigated the laboratory parameters in children admitted with febrile seizure and those with fever without localized sign (FWLS) in Shahid Motahari Hospital in Urmia. Methods. Demographic and clinical data of all patients admitted to the pediatric ward of Shahid Motahari Hospital in Urmia from 2015 to 2020 with febrile seizure and fever without localized sign (FWLS) were collected. Levels of BUN, creatinine, blood sugar, sodium, potassium , calcium , C reactive protein (CRP), neutrophil count, lymphocyte count, white blood cell count, hematocrit, platelets, ESR (Erythrocyte sedimentation rate ) and UA (urine analysis) and UC(urine cuiture), test results were also extracted from patients' file. Finally, the data extracted were compared between patients with febrile seizure and fever without localized sign (FWLS) cohort. Results. In this study, a total of 425 people were included, of which 185 were in the Febrile seizures group (case) and 240 were in the fever without localized sign (FWLS) (control) cohort, with 220 (51.8%) being male and 205 (48.2%) female. The mean age for all subjects was 20.62 ±4.84 months. There was a significant difference between the two groups in terms of mean levels of BUN (P=0.041), creatinine (P=0.006), ESR (P<0.001) and CRP (P<0.001); The mean levels of BUN and creatinine in patients with febrile seizures were significantly higher than patients with fever without localized sign (FWLS) and the mean ESR and CRP in patients with fever without localized sign (FWLS) were significantly higher than patients with febrile seizures. Conclusion. There is a significant difference in BUN, creatinine, ESR and CRP levels between patients with febrile seizure and fever without localized sign (FWLS), which can be used to predict the course of fever in children. Practical Implications. None of the laboratory parameters predict the onset of fever and seizures following a simple fever.https://mj.tbzmed.ac.ir/PDF/mj-44-47.pdflaboratory parametersfever without localized signfebrile seizure
spellingShingle Ezatollah Abbasi
Ahad Ghazavi
Asma Firoozi
Comparison of laboratory parameters in children admitted with febrile seizures and fever without localized sign in Urmia Motahari hospital, Iran, 2015 until 2020
مجله پزشکی دانشگاه علوم پزشکی تبریز
laboratory parameters
fever without localized sign
febrile seizure
title Comparison of laboratory parameters in children admitted with febrile seizures and fever without localized sign in Urmia Motahari hospital, Iran, 2015 until 2020
title_full Comparison of laboratory parameters in children admitted with febrile seizures and fever without localized sign in Urmia Motahari hospital, Iran, 2015 until 2020
title_fullStr Comparison of laboratory parameters in children admitted with febrile seizures and fever without localized sign in Urmia Motahari hospital, Iran, 2015 until 2020
title_full_unstemmed Comparison of laboratory parameters in children admitted with febrile seizures and fever without localized sign in Urmia Motahari hospital, Iran, 2015 until 2020
title_short Comparison of laboratory parameters in children admitted with febrile seizures and fever without localized sign in Urmia Motahari hospital, Iran, 2015 until 2020
title_sort comparison of laboratory parameters in children admitted with febrile seizures and fever without localized sign in urmia motahari hospital iran 2015 until 2020
topic laboratory parameters
fever without localized sign
febrile seizure
url https://mj.tbzmed.ac.ir/PDF/mj-44-47.pdf
work_keys_str_mv AT ezatollahabbasi comparisonoflaboratoryparametersinchildrenadmittedwithfebrileseizuresandfeverwithoutlocalizedsigninurmiamotaharihospitaliran2015until2020
AT ahadghazavi comparisonoflaboratoryparametersinchildrenadmittedwithfebrileseizuresandfeverwithoutlocalizedsigninurmiamotaharihospitaliran2015until2020
AT asmafiroozi comparisonoflaboratoryparametersinchildrenadmittedwithfebrileseizuresandfeverwithoutlocalizedsigninurmiamotaharihospitaliran2015until2020