Biguanide chitosan microneedles with cell-free DNA scavenging ability for psoriasis therapy

Biguanide chitosan microneedles with cell-free DNA scavenging ability for psoriasis therapy

High levels of cell-free DNA (cfDNA) induce psoriasis. Currently, the treatment of psoriasis has the disadvantages of penetration difficulty, suppression of normal immunity, and skin irritation. In this study, biguanide chitosan microneedles (BGC-MNs) were prepared to treat psoriasis by removing cfD...

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Bibliographic Details
Main Authors: Zihao Liu, Yu Wang, Yuhan Zhang, Liufu Hu, Bozhi Chen, Yang Li, Xindong Guo, Bingran Yu, Fu-Jian Xu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Bioactive Materials
Subjects:
Biguanide chitosan
cfDNA
Microneedles
Psoriasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23003857

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