Mesenchymal stem cells act as stimulators of neurogenesis and synaptic function in a rat model of Alzheimer's disease

Mesenchymal stem cells act as stimulators of neurogenesis and synaptic function in a rat model of Alzheimer's disease

Background: Alzheimer's disease (AD) is one of the most common NDs leading to cognitive dysfunctions and dementia which are progressively worsen with age. Cell therapy is currently of particular interest in treatment of neurodegenerative disease (ND) such as AD. However, the effective treatment...

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Bibliographic Details
Main Authors: Maryam Doshmanziari, Sadegh Shirian, Mohammad-Reza Kouchakian, Seyedeh Farzaneh Moniri, Saranaz Jangnoo, Niloofar Mohammadi, Fariba Zafari
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Heliyon
Subjects:
Alzheimer's disease
Synaptophysin
GAP43
Western blot
Flow cytometry
hUMSCs
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021020995

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