CLINICAL PRESENTATIONS AND COMPLICATIONS OF GUILLAIN BARRE SYNDROME IN CHILDREN WELFARE TEACHING HOSPITAL
Background: Guillain Barré syndrome is an acute inflammatory demyelinating disease of the peripheral nerves. Its synonyms are: acute inflammatory demyelinating polyradiculoneuropathy, idiopathic polyneuritis, acute infective polyneuropathy and post infections polyneuritis. Objectives: We attempt to...
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| Format: | Article |
| Language: | English |
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University of Baghdad/ Al-Kindy College of Medicine
2016-12-01
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| Series: | مجله كليه طب الكندي |
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| Online Access: | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/306 |
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| author | Mahjoob N. Al-Nadawi Husam Thaaban Al-Zuhairi Hafadh Jaleel Hussein Yusra Fayyadh Alwan |
| author_facet | Mahjoob N. Al-Nadawi Husam Thaaban Al-Zuhairi Hafadh Jaleel Hussein Yusra Fayyadh Alwan |
| author_sort | Mahjoob N. Al-Nadawi |
| collection | DOAJ |
| description |
Background: Guillain Barré syndrome is an acute inflammatory demyelinating disease of the peripheral nerves. Its synonyms are: acute inflammatory demyelinating polyradiculoneuropathy, idiopathic polyneuritis, acute infective polyneuropathy and post infections polyneuritis. Objectives: We attempt to study the clinical presentations and complications in patients with GBS who were admitted to children welfare Teaching Hospital and to compare the results with the other studies.Type of the study: A retrospective study.Methods: A study done on seventy patients with GBS who were admitted to children Welfare Teaching Hospital in Medical City-Baghdad from different parts of Iraq between January 2002-December 2006.Results: Forty (57.14%) of them were males and 30(42.86%) were females, a male to female ratio 1.33:1. There were more cases during winter months. Antecedent events were found in 44 patients (62.86%),26 patients (37.14%) had no history of antecedent events. It was found that 24 patients (34.3%) had only bilateral lower limbs weakness and 46 patients (65.7%) had both bilateral lower and upper limbs weakness. Sensory manifestations occurred in 35 patients (50%). Cranial nerves involvement was observed in 25 patients (35.7%). Autonomic nerves involvement was observed in 9 patients (12.9%). Respiratory muscles were involved in 20 patients (28.6%), 11 patients (15.7%) were admitted to the RCU and needed ventilator setting, 3 patients (4.28%) died in RCU. The results were compared with similar studies from other parts of the world.Conclusions: This study showed that there is no specific pattern of motor weakness involvement and all cases show symmetrical muscle weakness.Bulbar nerves (glossopharyngeal and vagus nerves) involvement is the commonest cranial nerve involvements.Autonomic nerves involvement and respiratory muscles involvement are the main cause of death in GBS. GBS patients should be admitted to the hospital and RCU with ventilator setting should be available along with well trained medical staff. Because the disease may run a prolonged course, we recommend close follow up of the patient to see the end result at that time.
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| first_indexed | 2024-04-11T21:18:57Z |
| format | Article |
| id | doaj.art-d25bf39699a94f31af501fd1d65aa38d |
| institution | Directory Open Access Journal |
| issn | 1810-9543 2521-4365 |
| language | English |
| last_indexed | 2024-04-11T21:18:57Z |
| publishDate | 2016-12-01 |
| publisher | University of Baghdad/ Al-Kindy College of Medicine |
| record_format | Article |
| series | مجله كليه طب الكندي |
| spelling | doaj.art-d25bf39699a94f31af501fd1d65aa38d2022-12-22T04:02:44ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652016-12-01122CLINICAL PRESENTATIONS AND COMPLICATIONS OF GUILLAIN BARRE SYNDROME IN CHILDREN WELFARE TEACHING HOSPITALMahjoob N. Al-Nadawi0Husam Thaaban Al-Zuhairi1Hafadh Jaleel Hussein2Yusra Fayyadh Alwan3Department of Paediatrics, College of Medicine- Baghdad UniversityIbn Al-Nafis cardiovascular teaching hospital., Baghdad, IraqIbn Al- Baladi Pediatrics and Maternity Hospital. Baghdad, IraqIbn Al- Baladi Pediatrics and Maternity Hospital. Baghdad, Iraq Background: Guillain Barré syndrome is an acute inflammatory demyelinating disease of the peripheral nerves. Its synonyms are: acute inflammatory demyelinating polyradiculoneuropathy, idiopathic polyneuritis, acute infective polyneuropathy and post infections polyneuritis. Objectives: We attempt to study the clinical presentations and complications in patients with GBS who were admitted to children welfare Teaching Hospital and to compare the results with the other studies.Type of the study: A retrospective study.Methods: A study done on seventy patients with GBS who were admitted to children Welfare Teaching Hospital in Medical City-Baghdad from different parts of Iraq between January 2002-December 2006.Results: Forty (57.14%) of them were males and 30(42.86%) were females, a male to female ratio 1.33:1. There were more cases during winter months. Antecedent events were found in 44 patients (62.86%),26 patients (37.14%) had no history of antecedent events. It was found that 24 patients (34.3%) had only bilateral lower limbs weakness and 46 patients (65.7%) had both bilateral lower and upper limbs weakness. Sensory manifestations occurred in 35 patients (50%). Cranial nerves involvement was observed in 25 patients (35.7%). Autonomic nerves involvement was observed in 9 patients (12.9%). Respiratory muscles were involved in 20 patients (28.6%), 11 patients (15.7%) were admitted to the RCU and needed ventilator setting, 3 patients (4.28%) died in RCU. The results were compared with similar studies from other parts of the world.Conclusions: This study showed that there is no specific pattern of motor weakness involvement and all cases show symmetrical muscle weakness.Bulbar nerves (glossopharyngeal and vagus nerves) involvement is the commonest cranial nerve involvements.Autonomic nerves involvement and respiratory muscles involvement are the main cause of death in GBS. GBS patients should be admitted to the hospital and RCU with ventilator setting should be available along with well trained medical staff. Because the disease may run a prolonged course, we recommend close follow up of the patient to see the end result at that time. https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/306Guillain Barré syndromeclinical presentationscomplications |
| spellingShingle | Mahjoob N. Al-Nadawi Husam Thaaban Al-Zuhairi Hafadh Jaleel Hussein Yusra Fayyadh Alwan CLINICAL PRESENTATIONS AND COMPLICATIONS OF GUILLAIN BARRE SYNDROME IN CHILDREN WELFARE TEACHING HOSPITAL مجله كليه طب الكندي Guillain Barré syndrome clinical presentations complications |
| title | CLINICAL PRESENTATIONS AND COMPLICATIONS OF GUILLAIN BARRE SYNDROME IN CHILDREN WELFARE TEACHING HOSPITAL |
| title_full | CLINICAL PRESENTATIONS AND COMPLICATIONS OF GUILLAIN BARRE SYNDROME IN CHILDREN WELFARE TEACHING HOSPITAL |
| title_fullStr | CLINICAL PRESENTATIONS AND COMPLICATIONS OF GUILLAIN BARRE SYNDROME IN CHILDREN WELFARE TEACHING HOSPITAL |
| title_full_unstemmed | CLINICAL PRESENTATIONS AND COMPLICATIONS OF GUILLAIN BARRE SYNDROME IN CHILDREN WELFARE TEACHING HOSPITAL |
| title_short | CLINICAL PRESENTATIONS AND COMPLICATIONS OF GUILLAIN BARRE SYNDROME IN CHILDREN WELFARE TEACHING HOSPITAL |
| title_sort | clinical presentations and complications of guillain barre syndrome in children welfare teaching hospital |
| topic | Guillain Barré syndrome clinical presentations complications |
| url | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/306 |
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