Melatonin alleviates valproic acid-induced neural tube defects by modulating Src/PI3K/ERK signaling and oxidative stress

Melatonin alleviates valproic acid-induced neural tube defects by modulating Src/PI3K/ERK signaling and oxidative stress

Neural tube defects (NTDs) represent a developmental disorder of the nervous system that can lead to significant disability in children and impose substantial social burdens. Valproic acid (VPA), a widely prescribed first-line antiepileptic...

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Bibliographic Details
Main Authors: Liang Yuxiang, Wang Ying, Zhang Xiao, Jin Shanshan, Guo Yuqian, Yu Zhaowei, Xu Xinrui, Shuai Qizhi, Feng Zihan, Chen Binghong, Liang Ting, Ao Ruifang, Li Jianting, Zhang Juan, Cao Rui, Zhao Hong, Chen Zhaoyang, Liu Zhizhen, Xie Jun
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2023-12-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
melatonin
valproic acid
neural tube defects
reactive oxygen species
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023234

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