Estetrol: From Preclinical to Clinical Pharmacology and Advances in the Understanding of the Molecular Mechanism of Action

Abstract Estetrol (E4) is the most recently described natural estrogen. It is produced by the human fetal liver during pregnancy and its physiological function remains unclear. E4 is the estrogenic component of a recently approved combined oral contraceptive. It is also in development for use as men...

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Bibliographic Details
Main Authors: Céline Gérard, Jean-Michel Foidart
Format: Article
Language:English
Published: Adis, Springer Healthcare 2023-05-01
Series:Drugs in R&D
Online Access:https://doi.org/10.1007/s40268-023-00419-5