Single-cell chromatin accessibility profiling of cell-state-specific gene regulatory programs during mouse organogenesis

Single-cell chromatin accessibility profiling of cell-state-specific gene regulatory programs during mouse organogenesis

In mammals, early organogenesis begins soon after gastrulation, accompanied by specification of various type of progenitor/precusor cells. In order to reveal dynamic chromatin landscape of precursor cells and decipher the underlying molecular mechanism driving early mouse organogenesis, we performed...

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Bibliographic Details
Main Authors: Qiuting Deng, Shengpeng Wang, Zijie Huang, Qing Lan, Guangyao Lai, Jiangshan Xu, Yue Yuan, Chang Liu, Xiumei Lin, Weimin Feng, Wen Ma, Mengnan Cheng, Shijie Hao, Shanshan Duan, Huiwen Zheng, Xiaoyan Chen, Yong Hou, Yingjie Luo, Longqi Liu, Chuanyu Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Neuroscience
Subjects:
mouse organogenesis
single-cell ATAC-seq
spinal cord
paraxial mesoderm
cis-regulatory elements
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1170355/full

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