Prevalence and pathologic effects of colibactin and cytotoxic necrotizing factor-1 (Cnf 1) in Escherichia coli: experimental and bioinformatics analyses
Abstract Background The colibactin and cytotoxic necrotizing factor 1 (Cnf 1) are toxins with cell cycle modulating effects that contribute to tumorgenesis and hyperproliferation. This study aimed to investigate the prevalence and pathologic effects of Cnf 1 and colibactin among hemolytic uropathoge...
Main Authors: | Radwa N. Morgan, Sarra E. Saleh, Hala A. Farrag, Mohammad M. Aboulwafa |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-05-01
|
Series: | Gut Pathogens |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13099-019-0304-y |
Similar Items
-
Cytotoxic necrotizing factor 1 hinders colon tumorigenesis induced by colibactin-producing Escherichia coli in ApcMin/+ mice
by: Héloïse Chat, et al.
Published: (2023-12-01) -
The Polyphosphate Kinase of <named-content content-type="genus-species">Escherichia coli</named-content> Is Required for Full Production of the Genotoxin Colibactin
by: Min Tang-Fichaux, et al.
Published: (2020-12-01) -
Colibactin: More Than a New Bacterial Toxin
by: Tiphanie Faïs, et al.
Published: (2018-04-01) -
Shining a Light on Colibactin Biology
by: Michael W. Dougherty, et al.
Published: (2021-05-01) -
Colibactin-producing Escherichia coli enhance resistance to chemotherapeutic drugs by promoting epithelial to mesenchymal transition and cancer stem cell emergence
by: Guillaume Dalmasso, et al.
Published: (2024-12-01)