Predictive Value of CHADS -VASc-HSF Score for Severity of Acute Coronary Syndrome
CHADS 2 and CHA 2 DS 2 -VASc scores have been used to assess the prognostic risk of thromboembolism in non-valvular atrial fibrillation patients. Recent studies have shown the utility of CHADS 2 and CHA 2 DS 2 -VASc scores for evaluating the severity of coronary artery disease (CAD). The newly defin...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-01-01
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| Series: | Clinical and Applied Thrombosis/Hemostasis |
| Online Access: | https://doi.org/10.1177/10760296211073969 |
| _version_ | 1818332467429376000 |
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| author | Jingyi Liu MM Yang Ma MM Haiwei Bu MM Wei Qin MM Fei Shi MM Ying Zhang MM |
| author_facet | Jingyi Liu MM Yang Ma MM Haiwei Bu MM Wei Qin MM Fei Shi MM Ying Zhang MM |
| author_sort | Jingyi Liu MM |
| collection | DOAJ |
| description | CHADS 2 and CHA 2 DS 2 -VASc scores have been used to assess the prognostic risk of thromboembolism in non-valvular atrial fibrillation patients. Recent studies have shown the utility of CHADS 2 and CHA 2 DS 2 -VASc scores for evaluating the severity of coronary artery disease (CAD). The newly defined CHA 2 DS 2 -VASc-HSF score evaluates atherosclerosis and is associated with CAD severity. This study investigated the association between the CHA 2 DS 2 -VASc-HSF score and acute coronary syndrome (ACS) severity as assessed by the Gensini score and the number of vessels. Furthermore, this study also compared the diagnostic value of the CHADS 2 , CHA2 DS2-VASc, and CHA 2 DS 2 -VASc-HSF score for ACS. A total of 2367 eligible inpatients (ACS group [ n = 2030]; non-CAD group [ n = 337]) were consecutively enrolled in this study. Receiver operating characteristic curve diagnostic tests and logistic regression models were used to analyze the risk factors for ACS. The CHADS 2 , CHA 2 DS 2 -VASc, and CHA 2 DS 2 -VASc-HSF scores were significantly higher in the ACS group than those in the control group. After adjusting for numerous traditional CAD risk factors, an increased CHA 2 DS 2 -VASc-HSF score was found to be an independent risk factor for patients with ACS (odds ratio 1.401, 95% confidence interval 1.044, −1.879; P < 0.05). A newly diagnosed CHA 2 DS 2 -VASc-HSF score predicts the severity of ACS. |
| first_indexed | 2024-12-13T13:36:12Z |
| format | Article |
| id | doaj.art-d2651315de534b47838a949c9710e755 |
| institution | Directory Open Access Journal |
| issn | 1938-2723 |
| language | English |
| last_indexed | 2024-12-13T13:36:12Z |
| publishDate | 2022-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical and Applied Thrombosis/Hemostasis |
| spelling | doaj.art-d2651315de534b47838a949c9710e7552022-12-21T23:43:48ZengSAGE PublishingClinical and Applied Thrombosis/Hemostasis1938-27232022-01-012810.1177/10760296211073969Predictive Value of CHADS -VASc-HSF Score for Severity of Acute Coronary SyndromeJingyi Liu MM0Yang Ma MM1Haiwei Bu MM2Wei Qin MM3Fei Shi MM4Ying Zhang MM5 , Chengde, HeBei, 067000, China , Chengde, HeBei, 067000, China , Chengde, HeBei, 067000, China , Chengde, HeBei, 067000, China , Chengde, HeBei, 067000, China , Chengde, HeBei, 067000, ChinaCHADS 2 and CHA 2 DS 2 -VASc scores have been used to assess the prognostic risk of thromboembolism in non-valvular atrial fibrillation patients. Recent studies have shown the utility of CHADS 2 and CHA 2 DS 2 -VASc scores for evaluating the severity of coronary artery disease (CAD). The newly defined CHA 2 DS 2 -VASc-HSF score evaluates atherosclerosis and is associated with CAD severity. This study investigated the association between the CHA 2 DS 2 -VASc-HSF score and acute coronary syndrome (ACS) severity as assessed by the Gensini score and the number of vessels. Furthermore, this study also compared the diagnostic value of the CHADS 2 , CHA2 DS2-VASc, and CHA 2 DS 2 -VASc-HSF score for ACS. A total of 2367 eligible inpatients (ACS group [ n = 2030]; non-CAD group [ n = 337]) were consecutively enrolled in this study. Receiver operating characteristic curve diagnostic tests and logistic regression models were used to analyze the risk factors for ACS. The CHADS 2 , CHA 2 DS 2 -VASc, and CHA 2 DS 2 -VASc-HSF scores were significantly higher in the ACS group than those in the control group. After adjusting for numerous traditional CAD risk factors, an increased CHA 2 DS 2 -VASc-HSF score was found to be an independent risk factor for patients with ACS (odds ratio 1.401, 95% confidence interval 1.044, −1.879; P < 0.05). A newly diagnosed CHA 2 DS 2 -VASc-HSF score predicts the severity of ACS.https://doi.org/10.1177/10760296211073969 |
| spellingShingle | Jingyi Liu MM Yang Ma MM Haiwei Bu MM Wei Qin MM Fei Shi MM Ying Zhang MM Predictive Value of CHADS -VASc-HSF Score for Severity of Acute Coronary Syndrome Clinical and Applied Thrombosis/Hemostasis |
| title | Predictive Value of CHADS -VASc-HSF Score for Severity of Acute Coronary Syndrome |
| title_full | Predictive Value of CHADS -VASc-HSF Score for Severity of Acute Coronary Syndrome |
| title_fullStr | Predictive Value of CHADS -VASc-HSF Score for Severity of Acute Coronary Syndrome |
| title_full_unstemmed | Predictive Value of CHADS -VASc-HSF Score for Severity of Acute Coronary Syndrome |
| title_short | Predictive Value of CHADS -VASc-HSF Score for Severity of Acute Coronary Syndrome |
| title_sort | predictive value of chads vasc hsf score for severity of acute coronary syndrome |
| url | https://doi.org/10.1177/10760296211073969 |
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