| Summary: | Background: kidney transplantation is a routine therapy in current medical practice. Survival of the renal graft varies depending on clinical and epidemiological factors, related to the donor, the organ preservation conditions and the recipient.
Objective: to determine survival and predictors of renal graft failure in patients treated in the Nephrology department of "Manuel Ascunce Domenech" Provincial Surgical-Clinical and Teaching Hospital, Camagüey, from 2000 to 2019.
Methods: a prospective longitudinal survival study was performed. The study population consisted of 260 patients transplanted with a cadaveric donor, who were followed until the loss of the graft or the end of the study. Graft survival was analyzed using the Kaplan-Meier method, survival curves were compared with the log-rank test, and Cox regression was used to determine the predictive variables of graft survival time.
Results: overall survival per year of renal grafts was 68.2 %; graft dysfunction was the complication with the highest incidence (25 %). Predictors of loss of renal graft function included: non-use of antilymphocyte antibodies, acute rejection, acute tubular necrosis, urinary tract infection and initial delayed function.
Conclusions: survival was determined and predictors of renal graft failure were identified in the study patients.
|
|---|