| Summary: | Purpose: Thrombotic complications have been reported in up to 30% of patients admitted to the intensive care unit for COVID-19. However, data on hemodialysis access failure in patients with COVID-19 are limited. This study aimed to investigate the frequency of hemodialysis access failure and its determinants, especially with respect to COVID-19 status.
Materials and Methods: This multi-center cross-sectional study was conducted among subjects undergoing permanent hemodialysis. Patients were divided into two groups, those with and without access failure. The primary outcome measures of the study were differences in patient characteristics, laboratory measurements and COVID-19 positivity between the two groups. The secondary outcome measure was defined as the identification of factors independently associated with hemodialysis access failure.
Results: Hemodialysis access failure occurred in 26 (12.2%) patients. Type 2 diabetes (76.9% [n=20] vs. 50% [n=93], p=0.018), hypotension during dialysis (88.5 [n=23] vs. 58.1% [n=108], p=0.006) and COVID-19 positivity (73.1% [n=19] vs. 15.1% [n=28], p<0.001) were significantly more frequent among patients with access failure. Multivariable logistic regression showed that all three factors were independently associated with a higher likelihood of hemodialysis access failure.
Conclusion: Hemodialysis access failure is encountered more frequently in patients with COVID-19 compared to those without COVID-19.
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