Primary thyroid gland myxofibrosarcoma: a case report and review of the literature
Abstract Background Myxofibrosarcoma is a common soft tissue sarcoma of the extremities, which occurs very rarely in the thyroid gland. Case presentation We report the case of a 61-year-old male who presented with a swelling of the left side of the neck and a newly emerged hoarseness. Ultrasound dep...
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2022-07-01
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| Series: | Surgical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40792-022-01496-5 |
| _version_ | 1828375012813307904 |
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| author | Maria Chara Stylianidi Lena Haeberle Matthias Schott Yuriko Mori Christina Antke Frederick Lars Giesel Gerald Antoch Irene Esposito Wolfram Trudo Knoefel Andreas Krieg |
| author_facet | Maria Chara Stylianidi Lena Haeberle Matthias Schott Yuriko Mori Christina Antke Frederick Lars Giesel Gerald Antoch Irene Esposito Wolfram Trudo Knoefel Andreas Krieg |
| author_sort | Maria Chara Stylianidi |
| collection | DOAJ |
| description | Abstract Background Myxofibrosarcoma is a common soft tissue sarcoma of the extremities, which occurs very rarely in the thyroid gland. Case presentation We report the case of a 61-year-old male who presented with a swelling of the left side of the neck and a newly emerged hoarseness. Ultrasound depicted a hypoechoic thyroid nodule with microcalcifications that was highly suspicious for malignancy. He underwent a left hemithyroidectomy. Histopathological examination and immunohistochemical studies revealed a myxofibrosarcoma of the thyroid gland. Conclusion Myxofibrosarcoma of the thyroid gland is extremely rare. The diagnosis is based on histopathological features. Radical surgery achieving tumor-free resection margins remains the only chance for cure. However, the role of radiotherapy and/or chemotherapy is still under debate. Due to their high tendency for locoregional recurrence, a close follow-up after surgery is mandatory. |
| first_indexed | 2024-04-14T07:41:46Z |
| format | Article |
| id | doaj.art-d26e181c99cb4dd5a4e272a8b39b0f16 |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-04-14T07:41:46Z |
| publishDate | 2022-07-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-d26e181c99cb4dd5a4e272a8b39b0f162022-12-22T02:05:29ZengSpringerOpenSurgical Case Reports2198-77932022-07-01811810.1186/s40792-022-01496-5Primary thyroid gland myxofibrosarcoma: a case report and review of the literatureMaria Chara Stylianidi0Lena Haeberle1Matthias Schott2Yuriko Mori3Christina Antke4Frederick Lars Giesel5Gerald Antoch6Irene Esposito7Wolfram Trudo Knoefel8Andreas Krieg9Department of Surgery (A), Medical Faculty, Heinrich-Heine-University and University Hospital DuesseldorfInstitute of Pathology, Medical Faculty, Heinrich-Heine-University and University Hospital DuesseldorfDivision for Specific Endocrinology, Medical Faculty, Heinrich-Heine-University and University Hospital DuesseldorfDepartment of Nuclear Medicine, Medical Faculty, Heinrich-Heine-University and University Hospital DuesseldorfDepartment of Nuclear Medicine, Medical Faculty, Heinrich-Heine-University and University Hospital DuesseldorfDepartment of Nuclear Medicine, Medical Faculty, Heinrich-Heine-University and University Hospital DuesseldorfDepartment of Diagnostic and Interventional Radiology, Medical Faculty, Heinrich-Heine-University and University Hospital DuesseldorfInstitute of Pathology, Medical Faculty, Heinrich-Heine-University and University Hospital DuesseldorfDepartment of Surgery (A), Medical Faculty, Heinrich-Heine-University and University Hospital DuesseldorfDepartment of Surgery (A), Medical Faculty, Heinrich-Heine-University and University Hospital DuesseldorfAbstract Background Myxofibrosarcoma is a common soft tissue sarcoma of the extremities, which occurs very rarely in the thyroid gland. Case presentation We report the case of a 61-year-old male who presented with a swelling of the left side of the neck and a newly emerged hoarseness. Ultrasound depicted a hypoechoic thyroid nodule with microcalcifications that was highly suspicious for malignancy. He underwent a left hemithyroidectomy. Histopathological examination and immunohistochemical studies revealed a myxofibrosarcoma of the thyroid gland. Conclusion Myxofibrosarcoma of the thyroid gland is extremely rare. The diagnosis is based on histopathological features. Radical surgery achieving tumor-free resection margins remains the only chance for cure. However, the role of radiotherapy and/or chemotherapy is still under debate. Due to their high tendency for locoregional recurrence, a close follow-up after surgery is mandatory.https://doi.org/10.1186/s40792-022-01496-5Soft tissue sarcomaMyxofibrosarcomaThyroid gland |
| spellingShingle | Maria Chara Stylianidi Lena Haeberle Matthias Schott Yuriko Mori Christina Antke Frederick Lars Giesel Gerald Antoch Irene Esposito Wolfram Trudo Knoefel Andreas Krieg Primary thyroid gland myxofibrosarcoma: a case report and review of the literature Surgical Case Reports Soft tissue sarcoma Myxofibrosarcoma Thyroid gland |
| title | Primary thyroid gland myxofibrosarcoma: a case report and review of the literature |
| title_full | Primary thyroid gland myxofibrosarcoma: a case report and review of the literature |
| title_fullStr | Primary thyroid gland myxofibrosarcoma: a case report and review of the literature |
| title_full_unstemmed | Primary thyroid gland myxofibrosarcoma: a case report and review of the literature |
| title_short | Primary thyroid gland myxofibrosarcoma: a case report and review of the literature |
| title_sort | primary thyroid gland myxofibrosarcoma a case report and review of the literature |
| topic | Soft tissue sarcoma Myxofibrosarcoma Thyroid gland |
| url | https://doi.org/10.1186/s40792-022-01496-5 |
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