SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which was rapidly declared a pandemic by the World Health Organization (WHO). Early clinical symptomatology focused mainly on respiratory illnesses. However, a variety of n...

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Bibliographic Details
Main Authors:	Pinar Mesci, Janaina S. de Souza, Laura Martin-Sancho, Angela Macia, Aurian Saleh, Xin Yin, Cedric Snethlage, Jason W. Adams, Simoni H. Avansini, Roberto H. Herai, Angels Almenar-Queralt, Yuan Pu, Ryan A. Szeto, Gabriela Goldberg, Patrick T. Bruck, Fabio Papes, Sumit K. Chanda, Alysson R. Muotri
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2022-11-01
Series:	PLoS Biology
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632769/?tool=EBI

SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir. by Pinar Mesci, Janaina S de Souza, Laura Martin-Sancho, Angela Macia, Aurian Saleh, Xin Yin, Cedric Snethlage, Jason W Adams, Simoni H Avansini, Roberto H Herai, Angels Almenar-Queralt, Yuan Pu, Ryan A Szeto, Gabriela Goldberg, Patrick T Bruck, Fabio Papes, Sumit K Chanda, Alysson R Muotri

Published 2022-11-01

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SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir

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