Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer
Breast cancer (BC) is one of the most common cancers in women worldwide; however, the successful treatment of BC, especially triple-negative breast cancer (TNBC), remains a significant clinical challenge. Recently, photothermal therapy (PTT), which involves the generation of heat under irradiation t...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Chemistry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2022.1024177/full |
| _version_ | 1811183751855603712 |
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| author | Jingjun Sun Jingjun Sun Haiyan Zhao Weixuan Xu Guo-Qin Jiang |
| author_facet | Jingjun Sun Jingjun Sun Haiyan Zhao Weixuan Xu Guo-Qin Jiang |
| author_sort | Jingjun Sun |
| collection | DOAJ |
| description | Breast cancer (BC) is one of the most common cancers in women worldwide; however, the successful treatment of BC, especially triple-negative breast cancer (TNBC), remains a significant clinical challenge. Recently, photothermal therapy (PTT), which involves the generation of heat under irradiation to achieve photothermal ablation of BC with minimal invasiveness and outstanding spatial–temporal selectivity, has been demonstrated as a novel therapy that can overcome the drawbacks of chemotherapy or surgery. Significantly, when combining PTT with chemotherapy and/or photodynamic therapy, an enhanced synergistic therapeutic effect can be achieved in both primary and metastatic BC tumors. Thus, this review discusses the recent developments in nanotechnology-based photothermal therapy for the treatment of BC and its metastasis to provide potential strategies for future BC treatment. |
| first_indexed | 2024-04-11T09:52:19Z |
| format | Article |
| id | doaj.art-d27116d48c2b475b98fd29b930c00176 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-11T09:52:19Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-d27116d48c2b475b98fd29b930c001762022-12-22T04:30:45ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462022-09-011010.3389/fchem.2022.10241771024177Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancerJingjun Sun0Jingjun Sun1Haiyan Zhao2Weixuan Xu3Guo-Qin Jiang4Department of Surgery, the Second Affiliated Hospital of Soochow University, Suzhou, ChinaDepartment of Breast Surgery, Affiliated Maternity and Child Health Care Hospital of Nantong University, Nantong, ChinaDepartment of Breast Surgery, Shanghai Changning Maternity and Infant Health Hospital, East China Normal University, Shanghai, ChinaDepartment of Breast Surgery, Affiliated Maternity and Child Health Care Hospital of Nantong University, Nantong, ChinaDepartment of Surgery, the Second Affiliated Hospital of Soochow University, Suzhou, ChinaBreast cancer (BC) is one of the most common cancers in women worldwide; however, the successful treatment of BC, especially triple-negative breast cancer (TNBC), remains a significant clinical challenge. Recently, photothermal therapy (PTT), which involves the generation of heat under irradiation to achieve photothermal ablation of BC with minimal invasiveness and outstanding spatial–temporal selectivity, has been demonstrated as a novel therapy that can overcome the drawbacks of chemotherapy or surgery. Significantly, when combining PTT with chemotherapy and/or photodynamic therapy, an enhanced synergistic therapeutic effect can be achieved in both primary and metastatic BC tumors. Thus, this review discusses the recent developments in nanotechnology-based photothermal therapy for the treatment of BC and its metastasis to provide potential strategies for future BC treatment.https://www.frontiersin.org/articles/10.3389/fchem.2022.1024177/fullbreast cancerphotothermal therapyaccurate therapytargeted delivery platformNIR dyecombination therapeutic strategy |
| spellingShingle | Jingjun Sun Jingjun Sun Haiyan Zhao Weixuan Xu Guo-Qin Jiang Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer Frontiers in Chemistry breast cancer photothermal therapy accurate therapy targeted delivery platform NIR dye combination therapeutic strategy |
| title | Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer |
| title_full | Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer |
| title_fullStr | Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer |
| title_full_unstemmed | Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer |
| title_short | Recent advances in photothermal therapy-based multifunctional nanoplatforms for breast cancer |
| title_sort | recent advances in photothermal therapy based multifunctional nanoplatforms for breast cancer |
| topic | breast cancer photothermal therapy accurate therapy targeted delivery platform NIR dye combination therapeutic strategy |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2022.1024177/full |
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